| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5233305 | A | Proteolytic stability assessed as recombinant human NEP-mediated compound degradation incubated for 24 hrs by LC-MS analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 2. | ALA5233306 | A | Stability in human plasma assessed as half life at 1 mM measured for 24 hrs by LC-MS analysis | Homo sapiens | 13 | cell-free format | Scientific Literature | ||
| 3. | ALA5233307 | A | Stability in mouse plasma assessed as half life at 1 mM measured for 24 hrs by LC-MS analysis | Mus musculus | 5 | cell-free format | Scientific Literature | ||
| 4. | ALA5233308 | A | Protein binding in pooled human plasma at 100 uM incubated for 3 hrs by equilibrium dialysis method | Homo sapiens | 5 | cell-free format | Scientific Literature | ||
| 5. | ALA5233309 | B | Displacement of [125I]-pyr-1-apelin-13 from EGFP tagged rat apelin receptor expressed in CHO cell membrane incubated for 3 hrs by gamma counter analysis | Rattus norvegicus | 13 | cell membrane format | Scientific Literature | ||
| 6. | ALA5233310 | B | Activation of recombinant human APJ receptor expressed in rat Chem-5 cells assessed as increase in Ca2+ mobilization by FLIPR Calcium 6-QF fluorescent dye based assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 7. | ALA5233311 | F | Hypotensive effect in anesthetized wild type mouse assessed as change in mean arterial blood pressure at 1.4 uM/Kg, iv administered via right jugular vein measured for 60 mins | Mus musculus | 13 | organism-based format | Scientific Literature | ||
| 8. | ALA5233312 | F | Hypotensive effect in anesthetized wild type mouse assessed as total time duration of hypotensive effect at 1.4 uM/Kg, iv administered via right jugular vein measured for 60 mins | Mus musculus | 13 | organism-based format | Scientific Literature |
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