# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5237721 | F | Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 24 hrs in nutrient-rich Dulbecco's modified Eagle's medium by WST-8 assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA5237722 | F | Preferential cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 24 hrs in nutrient-deprived medium by WST-8 assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
3. | ALA5237723 | T | Selectivity index, ratio of IC50 for cytotoxicity against human PANC-1 cells in nutrient-rich Dulbecco's modified Eagle's medium to PC50 for preferential cytotoxicity against human PANC-1 cells in nutrient-deprived medium | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
4. | ALA5237724 | F | Potency index, ratio of pipernonaline PC50 to test compound PC50 for Preferential cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 24 hrs in nutrient-deprived medium by WST-8 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA5237725 | B | Inhibition of Akt activation in human PANC-1 cells assessed as decrease in Akt phosphorylation at 5 uM incubated for 6 hrs in nutrient-deprived medium by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA5237726 | B | Inhibition of Akt activation in human PANC-1 cells assessed as effect on total Akt level at 1.25 to 5 uM incubated for 6 hrs in nutrient-deprived medium by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA5237727 | B | Inhibition of Akt activation in human PANC-1 cells assessed as effect on mTOR level at 1.25 to 5 uM incubated for 6 hrs in nutrient-deprived medium by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA5237728 | B | Inhibition of Akt activation in human PANC-1 cells assessed as effect on Atg3 level at 1.25 to 5 uM incubated for 6 hrs in nutrient-deprived medium by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5237729 | B | Inhibition of Akt activation in human PANC-1 cells assessed as effect on Atg7 level at 1.25 to 5 uM incubated for 6 hrs in nutrient-deprived medium by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5237730 | B | Inhibition of Akt activation in human PANC-1 cells assessed as upregulation of LC3-II level at 1.25 to 5 uM incubated for 6 hrs in nutrient-deprived medium by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5237731 | F | Inhibition of cell migration in human PANC-1 cells assessed as reduction in migration velocity at 20 uM measured every 15 min for 24 hrs in nutrient-rich Dulbecco's modified Eagle's medium by quantitative real-time cell migration assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5237732 | F | Inhibition of cell migration in human PANC-1 cells assessed as reduction in cell migration at 20 uM measured at 12 hrs in nutrient-rich Dulbecco's modified Eagle's medium by quantitative real-time cell migration assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA5237733 | F | Inhibition of cell migration in human PANC-1 cells assessed as reduction in cell migration at 20 uM measured at 18 hrs in nutrient-rich Dulbecco's modified Eagle's medium by quantitative real-time cell migration assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |