| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5265273 | B | Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire High Throughput Mass spectrometry | Homo sapiens | 63 | cell-based format | Scientific Literature | ||
| 2. | ALA5265274 | B | Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for 30 mins by RapidFire Mass spectrometry | Rattus norvegicus | 63 | cell-based format | Scientific Literature | ||
| 3. | ALA5265277 | A | Dose normalized AUC in mouse at 3 mg/kg, po | Mus musculus | 29 | organism-based format | Scientific Literature | ||
| 4. | ALA5265278 | A | Solubility of the compound in FaSSIF at pH 6.5 measured after 4 hrs by HPLC-UV analysis | 28 | assay format | Scientific Literature | |||
| 5. | ALA5265280 | A | Protein binding in human serum albumin by HPLC analysis | Homo sapiens | 27 | cell-free format | Scientific Literature | ||
| 6. | ALA5265416 | A | Half life in mouse S9 fraction pretreated for 5 mins followed by incubation with NADP for 30 secs and measured upto 45 mins by LC-MS/MS analysis | Mus musculus | 8 | subcellular format | Scientific Literature |
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