# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5225647 | B | Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 3 hrs without shaking by resorufin dye based fluorescence analysis | Homo sapiens | 34 | ALA5223163 | single protein format | Scientific Literature | |
2. | ALA5225648 | B | Inhibition of His-tagged human recombinant full length ME2 using L-malate and beta-NAD+ as substrate preincubated with enzyme for 5 mins followed by beta-NAD+ challenge and incubated under shaking for 5 mins followed by incubation for 2 hrs without shaking by resorufin dye based fluorescence analysis | Homo sapiens | 32 | ALA5223163 | single protein format | Scientific Literature | |
3. | ALA5225649 | B | Inhibition of His-tagged human recombinant full length ME1 using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 2 hrs without shaking by resorufin dye based fluorescence analysis | Homo sapiens | 32 | ALA5223163 | single protein format | Scientific Literature | |
4. | ALA5225654 | B | Selectivity ratio of IC50 for Inhibition of His-tagged human recombinant full length ME1 to IC50 for inhibition of His-tagged human recombinant ME3 (26 to 604 residues) | Homo sapiens | 2 | ALA5223163 | assay format | Scientific Literature | |
5. | ALA5225655 | B | Selectivity ratio of IC50 for Inhibition of His-tagged human recombinant full length ME2 to IC50 for inhibition of His-tagged human recombinant ME3 (26 to 604 residues) | Homo sapiens | 2 | ALA5223163 | assay format | Scientific Literature |