| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5225966 | ADME | Substrate activity at rat P-gp assessed as efflux ratio at 1 uM | Rattus norvegicus | 20 | ALA5223177 | assay format | Scientific Literature | |
| 2. | ALA5225968 | Binding | Inhibition of GCS in human fibroblast | Homo sapiens | 11 | ALA5223177 | cell-based format | Scientific Literature | |
| 3. | ALA5225969 | ADME | Substrate activity at mouse BCRP assessed as efflux ratio at 1 uM | Mus musculus | 9 | ALA5223177 | single protein format | Scientific Literature | |
| 4. | ALA5225970 | ADME | Substrate activity at mouse BCRP assessed as apparent permeability at 1 uM | Mus musculus | 9 | ALA5223177 | single protein format | Scientific Literature | |
| 5. | ALA5225971 | Binding | Antagonist activity at human 5HT3A expressed in HEK293 cells incubated for 1 hr by FLIPR assay | Homo sapiens | 9 | ALA5223177 | cell-based format | Scientific Literature | |
| 6. | ALA5225972 | Binding | Selectivity ratio of IC50 for human 5HT3A to IC50 for GCS (unknown origin) | Homo sapiens | 9 | ALA5223177 | assay format | Scientific Literature | |
| 7. | ALA5225973 | ADME | Clearance in rat at 5 to 10 mg/kg, po or 0.05 to 2 mg/kg, iv | Rattus norvegicus | 9 | ALA5223177 | organism-based format | Scientific Literature | |
| 8. | ALA5225974 | ADME | Intrinsic clearance in rat at 5 to 10 mg/kg, po or 0.05 to 2 mg/kg, iv | Rattus norvegicus | 9 | ALA5223177 | organism-based format | Scientific Literature | |
| 9. | ALA5225975 | ADME | Mean residence time in rat at 5 to 10 mg/kg, po or 0.05 to 2 mg/kg, iv | Rattus norvegicus | 9 | ALA5223177 | organism-based format | Scientific Literature | |
| 10. | ALA5225976 | ADME | Bioavailability in rat at 5 to 10 mg/kg, po or 0.05 to 2 mg/kg, iv | Rattus norvegicus | 9 | ALA5223177 | organism-based format | Scientific Literature |
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