| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5251557 | B | Antagonist activity at CXCR3 (unknown origin) in human T cells in venous blood assessed as receptor internalization incubated for 30 mins in presence of CXCL10 by flow cytometric analysis | Homo sapiens | 36 | ALA5247653 | cell-based format | Scientific Literature | |
| 2. | ALA5251558 | T | Inhibition of human ERG stably expressed in CHO cells at -80 mV holding voltage by automated QPatch electrophysiological assay | Homo sapiens | 36 | ALA5247653 | cell-based format | Scientific Literature | |
| 3. | ALA5251559 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM and measured upto 15 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 20 | ALA5247653 | microsome format | Scientific Literature | |
| 4. | ALA5251560 | A | Induction of recombinant human CYP2D6 mediated drug metabolism in human liver microsomes assessed as intrinsic clearance at 1 uM incubated for 45 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 9 | ALA5247653 | microsome format | Scientific Literature | |
| 5. | ALA5251561 | A | Induction of recombinant human CYP3A4 mediated drug metabolism in human liver microsomes assessed as intrinsic clearance at 1 uM incubated for 45 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 9 | ALA5247653 | microsome format | Scientific Literature | |
| 6. | ALA5251562 | P | Lipophilicity, log D of compound | 8 | ALA5247653 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA5251563 | A | Protein binding in human plasma assessed as fraction unbound at 1 uM incubated for 6 hrs by rapid equilibrium dialysis based LC-MS/MS analysis | Homo sapiens | 3 | ALA5247653 | cell-free format | Scientific Literature | |
| 8. | ALA5251564 | A | Protein binding in rat plasma assessed as fraction unbound at 1 uM incubated for 6 hrs by rapid equilibrium dialysis based LC-MS/MS analysis | Rattus norvegicus | 3 | ALA5247653 | cell-free format | Scientific Literature | |
| 9. | ALA5251565 | A | Protein binding in dog plasma assessed as fraction unbound at 1 uM incubated for 6 hrs by rapid equilibrium dialysis based LC-MS/MS analysis | Canis lupus familiaris | 3 | ALA5247653 | cell-free format | Scientific Literature | |
| 10. | ALA5251566 | A | Metabolic stability in rat liver microsomes assessed as intrinsic clearance at 1 uM and measured upto 15 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Rattus norvegicus | 3 | ALA5247653 | microsome format | Scientific Literature | |
| 11. | ALA5251567 | A | Metabolic stability in dog liver microsomes assessed as intrinsic clearance at 1 uM and measured upto 15 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Canis lupus familiaris | 3 | ALA5247653 | microsome format | Scientific Literature | |
| 12. | ALA5251568 | A | Metabolic stability in human hepatocytes assessed as intrinsic clearance per 10^6 cells at 1 uM by LC-MS/MS analysis | Homo sapiens | 3 | ALA5247653 | cell-based format | Scientific Literature | |
| 13. | ALA5251569 | A | Metabolic stability in rat hepatocytes assessed as intrinsic clearance per 10^6 cells at 1 uM by LC-MS/MS analysis | Rattus norvegicus | 3 | ALA5247653 | cell-based format | Scientific Literature | |
| 14. | ALA5251570 | A | Metabolic stability in dog hepatocytes assessed as intrinsic clearance per 10^6 cells at 1 uM by LC-MS/MS analysis | Canis lupus familiaris | 3 | ALA5247653 | cell-based format | Scientific Literature | |
| 15. | ALA5251571 | A | Total clearance in Wistar rat plasma at 0.5 mg/kg, iv | Rattus norvegicus | 3 | ALA5247653 | organism-based format | Scientific Literature | |
| 16. | ALA5251572 | A | Unbound clearance in Wistar rat plasma at 0.5 mg/kg, iv | Rattus norvegicus | 3 | ALA5247653 | organism-based format | Scientific Literature | |
| 17. | ALA5251573 | A | Total clearance in Beagle dog plasma at 1 mg/kg, iv | Canis lupus familiaris | 3 | ALA5247653 | organism-based format | Scientific Literature | |
| 18. | ALA5251574 | A | Unbound clearance in Beagle dog plasma at 1 mg/kg, iv | Canis lupus familiaris | 3 | ALA5247653 | organism-based format | Scientific Literature | |
| 19. | ALA5251577 | A | Drug excretion in urine of Wistar rat assessed as unchanged drug at 3 mg/kg, iv | Rattus norvegicus | 1 | ALA5247653 | organism-based format | Scientific Literature |
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