# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5249768 | F | Induction of morphological changes in human MX1 cells at 0.5 to 2 uM measured after 24 hrs by bright field inverted microscopic analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
2. | ALA5249769 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability by measuring release of nitrite at 100 uM after 180 mins by Griess reagent analysis | Homo sapiens | 15 | ALA5247609 | cell-based format | Scientific Literature | |
3. | ALA5249770 | F | Antiproliferative activity against human H460 cells assessed as reduction in cell viability after 96 hrs by MTT assay | Homo sapiens | 15 | ALA5247609 | cell-based format | Scientific Literature | |
4. | ALA5249771 | F | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 96 hrs by MTT assay | Homo sapiens | 15 | ALA5247609 | cell-based format | Scientific Literature | |
5. | ALA5249772 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 96 hrs by MTT assay | Homo sapiens | 15 | ALA5247609 | cell-based format | Scientific Literature | |
6. | ALA5249774 | F | Induction of morphological changes in human MDA-MB-231 cells at 0.5 to 2 uM measured after 24 hrs by bright field inverted microscopic analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
7. | ALA5249776 | F | Induction of morphological changes in human MX1 cells assessed as decrease in cell number at 0.5 to 2 uM measured after 24 hrs by bright field inverted microscopic analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
8. | ALA5249778 | F | Induction of morphological changes in human MDA-MB-231 cells assessed as decrease in cell number at 0.5 to 2 uM measured after 24 hrs by bright field inverted microscopic analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
9. | ALA5249780 | F | Induction of morphological changes in human MX1 cells assessed as decrease in cell size at 0.5 to 2 uM measured after 24 hrs by bright field inverted microscopic analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
10. | ALA5249782 | F | Induction of morphological changes in human MDA-MB-231 cells assessed as decrease in cell size at 0.5 to 2 uM measured after 24 hrs by bright field inverted microscopic analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
11. | ALA5249784 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as decrease in number of colony formation at 0.25 uM measured after 14 days by crystal violet staining based analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
12. | ALA5249786 | F | Induction of cell cycle arrest in human MX1 cells assessed as accumulation of cells at G0/G1 phase at 0.5 to 2 uM measured after 24 hrs by propidium iodide staining based FACS calibur flow cytometeric analysis (Rvb = 39.2%) | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
13. | ALA5249787 | F | Induction of cell cycle arrest in human MX1 cells assessed as decrease in accumulation of cells at S phase at 0.5 to 2 uM measured after 24 hrs by propidium iodide staining based FACS calibur flow cytometeric analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
14. | ALA5249788 | F | Induction of cell cycle arrest in human MX-1 cells assessed as accumulation of cells at G0/G1 phase incubated for 24 hrs by propidium iodide staining based FACS calibur flow cytometeric analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
15. | ALA5249789 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of cells at G0/G1 phase incubated for 24 hrs by propidium iodide staining based FACS calibur flow cytometeric analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
16. | ALA5249790 | F | Induction of cell cycle arrest in human MX1 cells assessed as increase in CDK6 expression at 0.5 to 2 uM by Western blotting analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
17. | ALA5249791 | F | Induction of cell cycle arrest in human MX1 cells assessed as decrease in cyclin B1 expression at 0.5 to 2 uM by Western blotting analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
18. | ALA5249792 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as increase in CDK6 expression at 0.5 to 2 uM by Western blotting analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
19. | ALA5249793 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as decrease in cyclin B1 expression at 0.5 to 2 uM by Western blotting analysis | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature | |
20. | ALA5249794 | F | Induction of apoptosis in human MX1 cells assessed as total apoptotic cells measured at 5 uM after 48 hrs by FITC-Annexin-V and propidium iodide based flow cytometric analysis (Rvb = 16.36%) | Homo sapiens | 1 | ALA5247609 | cell-based format | Scientific Literature |