# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5251531 | F | Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell growth with replenishment of medium with compound on day 4 and 7 by ATPlite assay | Homo sapiens | 6 | ALA5247652 | cell-based format | Scientific Literature | |
2. | ALA5251534 | B | Inhibition of N-terminal GST-tagged human recombinant G9a (785 to 1210 residues) expressed in baculovirus infected Sf9 cells incubated for 1 hr by AlphaLISA analysis | Homo sapiens | 57 | ALA5247652 | cell-based format | Scientific Literature | |
3. | ALA5251535 | P | Aqueous solubility of compound at pH 7.4 measured for 1 hr by UV-plate reader analysis | 26 | ALA5247652 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5251536 | A | Permeability of compound by PAMPA assay | 19 | ALA5247652 | assay format | Scientific Literature | ||
5. | ALA5251537 | A | Microsomal stability in mouse liver microsomes assessed as parent compound remaining after 30 mins in presence of NADPH by LC -MS/MS analysis | Mus musculus | 19 | ALA5247652 | microsome format | Scientific Literature | |
6. | ALA5251538 | A | Microsomal stability in human liver microsomes assessed as parent compound remaining after 30 mins in presence of NADPH by LC -MS/MS analysis | Homo sapiens | 19 | ALA5247652 | microsome format | Scientific Literature | |
7. | ALA5251539 | F | Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell growth with replenishment of medium with compound on day 4 and 7 and measured after 12 days by ATPlite assay | Homo sapiens | 6 | ALA5247652 | cell-based format | Scientific Literature | |
8. | ALA5251540 | F | Downregulation of H3K9 dimethylation in human MOLT-4 cells at 0.1 uM by Western blot analysis | Homo sapiens | 2 | ALA5247652 | cell-based format | Scientific Literature |