# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5251805 | B | PROTAC activity at VHL/SOS1 in human NCI-H358 cells harboring KRAS G12C mutant assessed as induction of SOS1 degradation upto 10 uM incubated for 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA5247656 | cell-based format | Scientific Literature | |
2. | ALA5251806 | B | PROTAC activity at VHL/SOS1 in human ASPC1 cells harboring KRAS G12D mutant assessed as induction of SOS1 degradation upto 10 uM incubated for 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA5247656 | cell-based format | Scientific Literature | |
3. | ALA5251851 | F | Antiproliferative activity against human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as inhibition of cell proliferation incubated for 7 days by CellTiterGlo-3D proliferation assay | Homo sapiens | 4 | ALA5247656 | cell-based format | Scientific Literature | |
4. | ALA5251852 | F | Antiproliferative activity against human NCI-H358 cells harboring KRAS G12C mutant assessed as inhibition of cell proliferation incubated for 7 days by CellTiterGlo-3D proliferation assay | Homo sapiens | 4 | ALA5247656 | cell-based format | Scientific Literature | |
5. | ALA5251853 | F | Antiproliferative activity against human ASPC1 cells harboring KRAS G12D mutant assessed as inhibition of cell proliferation incubated for 7 days by CellTiterGlo-3D proliferation assay | Homo sapiens | 4 | ALA5247656 | cell-based format | Scientific Literature | |
6. | ALA5251854 | F | Antiproliferative activity against human PANC-1 cells harboring KRAS G12D mutant assessed as inhibition of cell proliferation incubated for 7 days by CellTiterGlo-3D proliferation assay | Homo sapiens | 4 | ALA5247656 | cell-based format | Scientific Literature | |
7. | ALA5251855 | F | Antiproliferative activity against human SW620 cells harboring KRAS G12V mutant assessed as inhibition of cell proliferation incubated for 7 days by CellTiterGlo-3D proliferation assay | Homo sapiens | 4 | ALA5247656 | cell-based format | Scientific Literature | |
8. | ALA5251856 | F | Antiproliferative activity against human A549 cells harboring KRAS G12S mutant assessed as inhibition of cell proliferation incubated for 7 days by CellTiterGlo-3D proliferation assay | Homo sapiens | 4 | ALA5247656 | cell-based format | Scientific Literature | |
9. | ALA5251857 | F | Antiproliferative activity against human LoVo cells harboring KRAS G13D mutant assessed as inhibition of cell proliferation incubated for 7 days by CellTiterGlo-3D proliferation assay | Homo sapiens | 4 | ALA5247656 | cell-based format | Scientific Literature |