| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5239614 | B | Inhibition of GST-tagged bacterial beta-lactamase NMD-1 expressed in Escherichia coli BL21(DE3) using CCF2-FA as substrate by fluorescence assay | Bacteria | 21 | assay format | Scientific Literature | ||
| 2. | ALA5239615 | B | Inhibition of GST-tagged bacterial beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CCF2-FA as substrate by fluorescence assay | Bacteria | 21 | assay format | Scientific Literature | ||
| 3. | ALA5239616 | B | Inhibition of GST-tagged bacterial beta-lactamase VIM-1 expressed in Escherichia coli BL21(DE3) using CCF2-FA as substrate by fluorescence assay | Bacteria | 21 | assay format | Scientific Literature | ||
| 4. | ALA5239617 | F | Potentiation of imipenem-induced antibacterial activity against NDM-1 expressing Escherichia coli assessed as imipenem MIC incubated for 22 to 24 hrs (Rvb = 32 ug/ml) | Escherichia coli | 10 | organism-based format | Scientific Literature | ||
| 5. | ALA5239618 | F | Potentiation of imipenem-induced antibacterial activity against IMP-1 expressing Serratia marcescens assessed as imipenem MIC incubated for 22 to 24 hrs (Rvb = 16 ug/ml) | Serratia marcescens | 10 | organism-based format | Scientific Literature | ||
| 6. | ALA5239619 | F | Potentiation of imipenem-induced antibacterial activity against VIM-1 expressing Klebsiella pneumoniae assessed as imipenem MIC incubated for 22 to 24 hrs (Rvb = 16 ug/ml) | Klebsiella pneumoniae | 10 | organism-based format | Scientific Literature | ||
| 7. | ALA5239620 | U | Selectivity ratio of MITC50 for NDM-1 expressing Escherichia coli to IC50 for GST-tagged bacterial beta-lactamase NMD-1 | 10 | assay format | Scientific Literature | |||
| 8. | ALA5239621 | U | Selectivity ratio of MITC50 for IMP-1 expressing Serratia marcescens to IC50 for GST-tagged bacterial beta-lactamase IMP-1 | 10 | assay format | Scientific Literature | |||
| 9. | ALA5239622 | U | Selectivity ratio of MITC50 for VIM-1 expressing Klebsiella pneumoniae to IC50 for GST-tagged bacterial beta-lactamase VIM-1 | 9 | assay format | Scientific Literature | |||
| 10. | ALA5239623 | B | Displacement of MK499 from human ERG | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA5239624 | B | Inhibition of Nav1.5 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA5239625 | B | Inhibition of Cav1.5 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA5239626 | A | Reversible inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA5239627 | A | Reversible inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA5239628 | A | Reversible inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA5239629 | A | Selectivity ratio of time dependent inhibition of CYP3A4 (unknown origin) in presence of NADPH to time dependent inhibition of CYP3A4 (unknown origin) in absence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA5239630 | B | Inhibition of human PXR | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA5239631 | B | Inhibition of human PXR at 30 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5239632 | A | Plasma protein binding in C57BL/6 mouse assessed as unbound fraction | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 20. | ALA5239633 | A | Plasma protein binding in Wistar Han rat assessed as unbound fraction | Rattus norvegicus | 1 | cell-free format | Scientific Literature |
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