| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5237632 | F | Antiproliferative activity against human Bel-7402 cells incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA5236563 | cell-based format | Scientific Literature | |
| 2. | ALA5237633 | F | Antiproliferative activity against human BEL-7402/5-FU cells incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA5236563 | cell-based format | Scientific Literature | |
| 3. | ALA5237634 | F | Antiproliferative activity against human HepG2 cells incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA5236563 | cell-based format | Scientific Literature | |
| 4. | ALA5237635 | F | Antiproliferative activity against human HGC-27 cells incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA5236563 | cell-based format | Scientific Literature | |
| 5. | ALA5237636 | B | Inhibition of TrxR in human HGC-27 cells incubated for 72 hrs by microplate reader based analysis | Homo sapiens | 2 | ALA5236563 | cell-based format | Scientific Literature | |
| 6. | ALA5237637 | F | Induction of ROS accumulation in human BEL-7402/5-FU cells incubated for 24 hrs by FL1-H based flow cytometry analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 7. | ALA5237638 | F | Induction of apoptosis in human BEL-7402/5-FU cells assessed as reduction in mitochondrial transmembrane potential at 1 to 10 uM incubated for 24 hrs by JC-1 staining based microscopic analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 8. | ALA5237639 | F | Induction of DNA damage in human BEL-7402/5-FU cell assessed as increase in H2AX.S139ph expression at 1 to 3 uM incubated for 72 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 9. | ALA5237640 | F | Induction of DNA damage in human BEL-7402/5-FU cell assessed as increase in p53 expression at 1 to 3 uM incubated for 72 hrs by Western blotting analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 10. | ALA5237641 | F | Induction of autophagy in human BEL-7402/5-FU cells harboring GFP-mRFP-LC3 assessed as increase in LC3 level at 1 to 3 uM incubated for 24 hrs by confocal microscopy based analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 11. | ALA5237642 | F | Induction of autophagy in human BEL-7402/5-FU cells harboring GFP-mRFP-LC3 assessed as increase in p62 level at 1 to 3 uM incubated for 24 hrs by confocal microscopy based analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 12. | ALA5237643 | F | Induction of autophagy in human BEL-7402/5-FU cells harboring GFP-mRFP-LC3 assessed as increase in beclin-1 level at 1 to 3 uM incubated for 24 hrs by confocal microscopy based analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 13. | ALA5237644 | F | Upregulation of LC3-II level in human BEL-7402/5-FU cells at 0.3 to 3 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 14. | ALA5237645 | F | Upregulation of beclin-1 level in human BEL-7402/5-FU cells at 0.3 to 3 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 15. | ALA5237646 | F | Downregulation of p62 level in human BEL-7402/5-FU cells at 0.3 to 3 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA5236563 | cell-based format | Scientific Literature | |
| 16. | ALA5237647 | T | Acute toxicity in ICR mouse assessed as mouse death at 303.8 mg/kg, ip administered as single dose measured after 1 hr | Mus musculus | 1 | ALA5236563 | organism-based format | Scientific Literature | |
| 17. | ALA5237648 | T | Acute toxicity in ICR mouse assessed as mouse death at 202.5 mg/kg, ip administered as single dose measured after 1 hr | Mus musculus | 1 | ALA5236563 | organism-based format | Scientific Literature | |
| 18. | ALA5237649 | T | Acute toxicity in ICR mouse assessed as mouse death at 202.5 mg/kg, ip administered as single dose measured after 4 hrs | Mus musculus | 1 | ALA5236563 | organism-based format | Scientific Literature | |
| 19. | ALA5237650 | T | Acute toxicity in ICR mouse assessed as mouse death at 135 mg/kg, ip administered as single dose measured after 1 hrs | Mus musculus | 1 | ALA5236563 | organism-based format | Scientific Literature | |
| 20. | ALA5237651 | T | Acute toxicity in ICR mouse assessed as mouse death at 135 mg/kg, ip administered as single dose measured after 4 hrs | Mus musculus | 1 | ALA5236563 | organism-based format | Scientific Literature |
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