# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5229870 | Functional | Antiproliferative activity against human LNCaP cells assessed as reduction in cell viability incubated for 45 mins by gamma counter analysis | Homo sapiens | 11 | ALA5226383 | cell-based format | Scientific Literature | |
2. | ALA5253198 | Binding | Binding affinity to PSMA in human LNCaP cells after 45 mins in presence of 68Ga-labeled PSMA-10 by gamma counting assay | Homo sapiens | 19 | ALA5252516 | cell-based format | Scientific Literature | |
3. | ALA5253199 | Physicochemical | Retention time of the compound by HPLC | 19 | ALA5252516 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5253200 | Physicochemical | Distribution coefficient, logD of the compound at pH 7.4 in n-octanol/0.1 M HEPES by shake flask method | 19 | ALA5252516 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA5253201 | Binding | Inhibition of PSMA in human LNCaP cells assessed as cell surface binding per 10^6 cells using 177Lu-labeled compound after 45 mins by gamma counting analysis | Homo sapiens | 19 | ALA5252516 | cell-based format | Scientific Literature | |
6. | ALA5253202 | Binding | Inhibition of PSMA in human LNCaP cells assessed as specific internalization per 10^6 cells using 177Lu-labeled compound after 45 mins by gamma counting analysis | Homo sapiens | 19 | ALA5252516 | cell-based format | Scientific Literature | |
7. | ALA5253203 | ADME | Drug uptake in iv dosed BALB/c athymic nude mouse tumor xenografted with human LNCaP cells treated with 68Ga-labeled compound measured after 1 hr by microPET imaging analysis | Mus musculus | 19 | ALA5252516 | organism-based format | Scientific Literature | |
8. | ALA5253204 | ADME | Drug uptake in iv dosed BALB/c athymic nude mouse muscle xenografted with human LNCaP cells treated with 68Ga-labeled compound measured after 1 hr by microPET imaging analysis | Mus musculus | 19 | ALA5252516 | organism-based format | Scientific Literature | |
9. | ALA5253205 | ADME | Drug uptake in iv dosed BALB/c athymic nude mouse kidney xenografted with human LNCaP cells treated with 68Ga-labeled compound measured after 1 hr by microPET imaging analysis | Mus musculus | 19 | ALA5252516 | organism-based format | Scientific Literature | |
10. | ALA5253206 | ADME | Ratio of drug uptake in tumor to muscle in iv dosed BALB/c athymic nude mouse xenografted with human LNCaP cells treated with 68Ga-labeled compound measured after 1 hr by microPET imaging analysis | Mus musculus | 19 | ALA5252516 | organism-based format | Scientific Literature | |
11. | ALA5253208 | ADME | Drug uptake in iv dosed BALB/c athymic nude mouse tumor xenografted with human LNCaP cells treated with 68Ga-labeled compound measured upto 120 mins by microPET imaging analysis | Mus musculus | 15 | ALA5252516 | organism-based format | Scientific Literature |