# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5265706 | Functional | Antitumor activity against human MDA-MB-435 cells xenografted in nude mouse at 50 mg/kg, ip administered 3 times a week for 2 weeks and measured on day 14 | Homo sapiens | 1 | ALA5260860 | organism-based format | Scientific Literature | |
2. | ALA5265708 | Functional | Antitumor activity against human MDA-MB-435 cells xenografted in nude mouse assessed as reduction in tumor volume at 50 mg/kg, ip administered 3 times a week for 2 weeks and measured on day 14 | Homo sapiens | 1 | ALA5260860 | organism-based format | Scientific Literature | |
3. | ALA5265709 | Functional | Relative resistance, ratio of IC50 for antiproliferative activity against human SK-OV-3 cells overexpressing MDR-1-M6/6 to IC50 for antiproliferative activity against human SK-OV-3 cells | Homo sapiens | 20 | ALA5260860 | cell-based format | Scientific Literature | |
4. | ALA5265710 | Functional | Antiproliferative activity against human SK-OV-3 cells overexpressing MDR-1-M6/6 assessed as inhibition of cell growth by SRB assay | Homo sapiens | 20 | ALA5260860 | cell-based format | Scientific Literature | |
5. | ALA5265711 | Functional | Antiproliferative activity against wild type human SK-OV-3 cells assessed as inhibition of cell growth by SRB assay | Homo sapiens | 20 | ALA5260860 | cell-based format | Scientific Literature | |
6. | ALA5265712 | Functional | Relative resistance, ratio of IC50 for antiproliferative activity against human HeLa cells overexpressing betaIII-tubulin to IC50 for antiproliferative activity against wild type human HeLa cells | Homo sapiens | 20 | ALA5260860 | cell-based format | Scientific Literature | |
7. | ALA5265713 | Functional | Antiproliferative activity against human HeLa cells overexpressing betaIII-tubulin assessed as inhibition of cell growth by SRB assay | Homo sapiens | 20 | ALA5260860 | cell-based format | Scientific Literature | |
8. | ALA5265714 | Functional | Antiproliferative activity against wild type human HeLa cells assessed as inhibition of cell growth by SRB assay | Homo sapiens | 20 | ALA5260860 | cell-based format | Scientific Literature | |
9. | ALA5265716 | Binding | Displacement of [3H]colchicine from bovine brain tubulin at 5 uM incubated for 10 mins | Bos taurus | 20 | ALA5260860 | tissue-based format | Scientific Literature | |
10. | ALA5265718 | Unassigned | Selectivity ratio of EC50 for induction of microtubule depolymerization in rat A10 cells to IC50 for antiproliferative activity against human MDA-MB-435 cells | 19 | ALA5260860 | cell-based format | Scientific Literature | ||
11. | ALA5265719 | Binding | Induction of microtubule depolymerization in rat A10 cells incubated for 18 hrs by indirect immunofluorescence analysis | Rattus norvegicus | 20 | ALA5260860 | cell-based format | Scientific Literature | |
12. | ALA5265720 | Functional | Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition of cell growth by SRB assay | Homo sapiens | 21 | ALA5260860 | cell-based format | Scientific Literature |