# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5223347 | T | Cytotoxicity against human monocytes assessed as reduction in cell viability at 0.01 to 10 uM incubated for 1 to 6 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
2. | ALA5223348 | F | Induction of IL-6 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA5223349 | F | Induction of IL-1beta mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA5223350 | F | Induction of TNF-alpha mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA5223351 | F | Induction of IL-10 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA5223359 | F | Modulation of LPS-induced IL-6 mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA5223360 | F | Modulation of LPS-induced IL-1beta mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA5223361 | F | Modulation of LPS-induced TNF-alpha mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA5223362 | F | Modulation of LPS-induced IL-10 mRNA expression in human monocytes at 7.5 nM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
10. | ALA5223367 | F | Modulation of COX-1 mRNA expression in human monocytes at 7.5 nM incubated for 1 hr by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
11. | ALA5223369 | B | Inhibition of human COX-1 at 0.1 to 50 nM by spectrophotometer analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
12. | ALA5223373 | F | Induction of superoxide anion production in human monocytes assessed as increase in reduced cytochrome C level at 0.0025 to 1 uM incubated for 1 hr | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
13. | ALA5223374 | F | Inhibition of PMA-induced oxidative burst in human monocytes at 0.1 to 50 nM preincubated for 1 hr followed by PMA stimulation and measured after 30 mins relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
14. | ALA5223375 | F | Inhibition of PMA-induced oxidative burst in human monocytes preincubated for 1 hr followed by PMA stimulation and measured after 30 mins | Homo sapiens | 5 | cell-based format | Scientific Literature |