# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5254198 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced IkappaBalpha protein expression level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
2. | ALA5254477 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced IkappaBalpha phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
3. | ALA5254517 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced JNK phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
4. | ALA5254518 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced p-38 phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
5. | ALA5254519 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced ERK phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
6. | ALA5254593 | B | Antagonist activity at NOD1 in human HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced SEAP release preincubated for 3 hrs followed by C12-iE-DAP addition incubated for 20 hrs by spectrophotometer assay | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
7. | ALA5254594 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced IkappaBalpha phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
8. | ALA5254595 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced ERK phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
9. | ALA5254596 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced p-38 phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
10. | ALA5254597 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced JNK phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
11. | ALA5254598 | B | Antagonist activity at NOD1 in human THP-1 cells assessed as decrease in C12-iE-DAP-induced IkappaBalpha protein expression level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
12. | ALA5254599 | T | Cytotoxicity against human HEK-Blue hNOD1 cells by sulforhodamine B assay | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
13. | ALA5254600 | F | Cytotoxicity against human THP-1 cells by sulforhodamine B assay | Homo sapiens | 1 | ALA5252546 | cell-based format | Scientific Literature | |
14. | ALA5254601 | T | Cytotoxicity against mouse peritoneal macrophage by sulforhodamine B assay | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
15. | ALA5254602 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced IkappaBalpha phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
16. | ALA5254603 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced ERK phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
17. | ALA5254604 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced p-38 phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
18. | ALA5254605 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced JNK phosphorylation level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
19. | ALA5254606 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced IkappaBalpha protein expression level at 1 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature | |
20. | ALA5254607 | B | Antagonist activity at NOD1 in mouse peritoneal macrophage assessed as decrease in C12-iE-DAP-induced IkappaBalpha phosphorylation level at 10 uM incubated for 1 hr followed by C12-iE-DAP addition and measured for 1 hr by western blot analysis | Mus musculus | 1 | ALA5252546 | cell-based format | Scientific Literature |