| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5251238 | B | Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) at 1 uM incubated for 180 mins by competitive radioligand binding assay (Rvb = 1.3 %) | Homo sapiens | 24 | ALA5247645 | single protein format | Scientific Literature | |
| 2. | ALA5251239 | B | Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) at 1 uM incubated for 180 mins by competitive radioligand binding assay (Rvb = 0.6 %) | Homo sapiens | 24 | ALA5247645 | single protein format | Scientific Literature | |
| 3. | ALA5251240 | B | Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) at 10 uM incubated for 180 mins by competitive radioligand binding assay (Rvb = 1.9 %) | Homo sapiens | 24 | ALA5247645 | single protein format | Scientific Literature | |
| 4. | ALA5251241 | B | Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) at 10 uM incubated for 180 mins by competitive radioligand binding assay (Rvb = 0.6 %) | Homo sapiens | 24 | ALA5247645 | single protein format | Scientific Literature | |
| 5. | ALA5251242 | B | Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand binding assay | Homo sapiens | 8 | ALA5247645 | single protein format | Scientific Literature | |
| 6. | ALA5251243 | B | Displacement of [3H]-U69593 from kappa opioid receptor (unknown origin) assessed as inhibition constant incubated for 180 mins by competitive radioligand binding assay | Homo sapiens | 8 | ALA5247645 | single protein format | Scientific Literature | |
| 7. | ALA5251244 | B | Selectivity ratio of Ki for kappa opioid receptor (unknown origin) to Ki for mu opioid receptor (unknown origin) | Homo sapiens | 7 | ALA5247645 | assay format | Scientific Literature | |
| 8. | ALA5251245 | B | Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by Glo Sensor assay | Mus musculus | 8 | ALA5247645 | cell-based format | Scientific Literature | |
| 9. | ALA5251246 | B | Agonist activity at HA-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by Glo Sensor assay relative to control | Mus musculus | 8 | ALA5247645 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!