# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5238554 | B | Binding affinity to glucocorticoid receptor (unknown origin) by Lanthascreen TR-FRET competition binding assay | Homo sapiens | 65 | single protein format | Scientific Literature | ||
2. | ALA5238555 | B | Modulation of glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as transrepression by measuring inhibition of TNF-alpha induced NF-kappaB signalling incubated for 18 hrs by dual-luciferase reporter based assay | Homo sapiens | 64 | cell-based format | Scientific Literature | ||
3. | ALA5238556 | B | Modulation of glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as transrepression by measuring inhibition of PMA-induced AP-1 signalling incubated for 18 hrs by dual-luciferase reporter based assay | Homo sapiens | 64 | cell-based format | Scientific Literature | ||
4. | ALA5238558 | B | Antagonist activity at glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as inhibition of dexamethasone-induced transactivation of receptor incubated for 18 hrs by firefly luciferase assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
5. | ALA5238559 | B | Agonist activity at glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as transactivation of receptor at 10 uM incubated for 18 hrs by firefly luciferase assay | Homo sapiens | 63 | cell-based format | Scientific Literature | ||
6. | ALA5238561 | F | Antiinflammatory activity against LPS-induced mouse RAW264.7 cells assessed as reduction in IL-6 mRNA expression at 10 uM by RT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
7. | ALA5238562 | F | Antiinflammatory activity against LPS-induced mouse RAW264.7 cells assessed as reduction in IL-1beta mRNA expression at 10 uM by RT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
8. | ALA5238563 | F | Antiinflammatory activity against LPS-induced mouse RAW264.7 cells assessed as reduction in TSLP mRNA expression at 10 uM by RT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
9. | ALA5238564 | F | Antiinflammatory activity against LPS-induced mouse RAW264.7 cells assessed as reduction in MMP-13 mRNA expression at 10 uM by RT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
10. | ALA5238565 | F | Antiinflammatory activity against LPS-induced mouse RAW264.7 cells assessed as reduction in TNF-alpha mRNA expression at 10 uM by RT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
11. | ALA5238566 | F | Antiinflammatory activity against LPS-induced mouse RAW264.7 cells assessed as reduction in CCL-2 mRNA expression at 10 uM by RT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
12. | ALA5238567 | F | Upregulation of GILZ transcription in LPS-induced mouse RAW264.7 cells at 10 uM by RT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
13. | ALA5238568 | F | Inhibition of LPS-induced IL-6 secretion in mouse primary peritoneal macrophages by ELISA | Mus musculus | 2 | cell-based format | Scientific Literature | ||
14. | ALA5238569 | F | Inhibition of LPS-induced TNF-alpha secretion in mouse primary peritoneal macrophages by ELISA | Mus musculus | 2 | cell-based format | Scientific Literature | ||
15. | ALA5238570 | B | Activation of androgen receptor (unknown origin) transfected in human LNCaP cells incubated for 18 hrs by fluorescence based analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA5238571 | B | Activation of human progesterone receptor transfected in human PC-3 cells incubated for 16 hrs by luciferase based analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA5238572 | B | Activation of human mineralocorticoid receptor transfected in HEK293T cells incubated for 16 hrs by luciferase based analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA5238574 | T | Cytotoxicity against mouse 3T3 cells assessed as inhibition of cell growth | Mus musculus | 2 | cell-based format | Scientific Literature | ||
19. | ALA5238575 | T | Cytotoxicity against human GES1 cells assessed as inhibition of cell growth | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
20. | ALA5238577 | A | Cmax in BALB/c mouse at 10 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature |