| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5238624 | F | Antiviral activity against wild type HIV-1 IIIB infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 46 | ALA5236598 | organism-based format | Scientific Literature | |
| 2. | ALA5238625 | F | Antiviral activity against HIV-1 RES056 harboring RT K103N/Y181C double mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 46 | ALA5236598 | organism-based format | Scientific Literature | |
| 3. | ALA5238626 | T | Cytotoxicity against human MT4 cells assessed as reduction in cell viability measured after 5 days by MTT assay | Homo sapiens | 46 | ALA5236598 | cell-based format | Scientific Literature | |
| 4. | ALA5238627 | T | Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells to EC50 for antiviral activity against wild type HIV-1 IIIB infected in human MT4 cells | 46 | ALA5236598 | cell-based format | Scientific Literature | ||
| 5. | ALA5238628 | T | Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells to EC50 for antiviral activity against HIV-1 RES056 harboring RT K103N/Y181C double mutant infected in human MT4 cells | 46 | ALA5236598 | cell-based format | Scientific Literature | ||
| 6. | ALA5238629 | F | Antiviral activity against HIV-1 harboring RT L100I mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 6 | ALA5236598 | organism-based format | Scientific Literature | |
| 7. | ALA5238630 | F | Antiviral activity against HIV-1 harboring RT K103N mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 6 | ALA5236598 | organism-based format | Scientific Literature | |
| 8. | ALA5238631 | F | Antiviral activity against HIV-1 harboring RT Y181C mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 6 | ALA5236598 | organism-based format | Scientific Literature | |
| 9. | ALA5238632 | F | Antiviral activity against HIV-1 harboring RT Y188L mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 6 | ALA5236598 | organism-based format | Scientific Literature | |
| 10. | ALA5238633 | F | Antiviral activity against HIV-1 harboring RT E138K mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 6 | ALA5236598 | organism-based format | Scientific Literature | |
| 11. | ALA5238634 | F | Antiviral activity against HIV-1 harboring RT F227L/V106A double mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 6 | ALA5236598 | organism-based format | Scientific Literature | |
| 12. | ALA5238635 | F | Potency index, ratio of Etravirine EC50 to test compound EC50 for antiviral activity against HIV-1 harboring RT K103N mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 1 | ALA5236598 | organism-based format | Scientific Literature | |
| 13. | ALA5238636 | F | Potency index, ratio of Etravirine EC50 to test compound EC50 for antiviral activity against HIV-1 harboring RT E138K mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect incubated for 5 days by MTT assay | Human immunodeficiency virus 1 | 1 | ALA5236598 | organism-based format | Scientific Literature | |
| 14. | ALA5238638 | B | Inhibition of wild type recombinant HIV-1 reverse transcriptase using biotin-labelled dNTPs as substrate assessed as inhibition of biotin-labelled UTP incorporation incubated for 1 hr by ELISA | Human immunodeficiency virus 1 | 5 | ALA5236598 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!