#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5244397	ADME	Clearance in Sprague-Dawley rat at 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
2.	ALA5244398	ADME	Volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
3.	ALA5244399	ADME	Half life in Sprague-Dawley rat at 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
4.	ALA5244400	ADME	AUC (0 to 24 hrs) in Sprague-Dawley rat at 1 mg/kg, iv measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
5.	ALA5244401	ADME	Cmax in Sprague-Dawley rat at 1 mg/kg, po measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
6.	ALA5244402	ADME	Half life in Sprague-Dawley rat at 1 mg/kg, po measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
7.	ALA5244403	ADME	AUC (0 to 24 hrs) in Sprague-Dawley rat at 1 mg/kg, po measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
8.	ALA5244404	ADME	Oral availability in Sprague-Dawley rat at 1 mg/kg measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
9.	ALA5244405	ADME	Tmax in Sprague-Dawley rat at 1 mg/kg, po measured up to 24 hrs by LC-MS/MS analysis	Rattus norvegicus	3	ALA5244205	organism-based format	Scientific Literature
10.	ALA5244406	Binding	Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA	Homo sapiens	15	ALA5244205	single protein format	Scientific Literature
11.	ALA5244407	Binding	Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA	Homo sapiens	15	ALA5244205	single protein format	Scientific Literature
12.	ALA5244408	Binding	Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA	Homo sapiens	12	ALA5244205	single protein format	Scientific Literature
13.	ALA5244409	ADME	Intrinsic clearance in Sprague-Dawley rat liver microsomes at 0.2 uM incubated for 45 mins in presence of NADPH by LC-MS/MS analysis	Rattus norvegicus	10	ALA5244205	microsome format	Scientific Literature
14.	ALA5244410	ADME	Time-dependent inhibition of CYP3A4 in human liver microsomes at 5 uM using midazolam as substrate preincubated for 0 to 30 mins followed by midazolam addition and measured after 20 mins by LC-MS/MS analysis relative to control	Homo sapiens	13	ALA5244205	microsome format	Scientific Literature
15.	ALA5244411	ADME	Permeability of the compound in pH 6.5 incubated for 2 hrs by PAMPA based HPLC analysis		15	ALA5244205	assay format	Scientific Literature
16.	ALA5244412	Functional	Immunosuppressive activity in Lewis rat splenocytes assessed as inhibition of concanavalin A-induced IL-2 receptor expression incubated for 3 days by alamarBlue assay	Rattus norvegicus	2	ALA5244205	cell-based format	Scientific Literature
17.	ALA5244413	Binding	Selectivity index, ratio of IC50 for human JAK3 to IC50 for human JAK2	Homo sapiens	2	ALA5244205	assay format	Scientific Literature
18.	ALA5244414	Binding	Inhibition of ABL (unknown origin)	Homo sapiens	2	ALA5244205	single protein format	Scientific Literature
19.	ALA5244415	Binding	Inhibition of BTK (unknown origin)	Homo sapiens	2	ALA5244205	single protein format	Scientific Literature
20.	ALA5244416	Binding	Inhibition of CSK (unknown origin)	Homo sapiens	2	ALA5244205	single protein format	Scientific Literature