| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5261286 | F | Antiviral activity against Influenza A virus A/PR/8/34 infected in MDCK cells assessed as reduction in viral RNA level incubated for 20 hrs by bDNA hybridization method | Influenza A virus | 13 | organism-based format | Scientific Literature | ||
| 2. | ALA5261287 | B | Binding affinity to full length Influenza A virus PB2 cap-binding domain assessed as dissociation constant incubated for 60 mins by fluorescence polarization assay | influenza A virus | 13 | single protein format | Scientific Literature | ||
| 3. | ALA5261291 | A | AUC in mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA5261292 | A | Cmax in mouse at 30 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA5261293 | A | Stability in rat S9 fraction assessed as compound remaining at 1 uM | Rattus norvegicus | 1 | subcellular format | Scientific Literature | ||
| 6. | ALA5261294 | A | Stability in human S9 fraction assessed as compound remaining at 1 uM | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 7. | ALA5261303 | F | Antiviral activity against Influenza A virus A/PR/8/34 infected in BALB/C mouse model assessed as increase in survival at 10 to 60 mg/kg, po administered twice daily for 10 days from 48 hrs post-infection and measured for 21 days | Influenza A virus | 2 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!