#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5225738	A	Metabolic stability in mouse liver microsomes assessed as parent compound remaining measured for 2 hrs by HPLC analysis	Mus musculus	3	ALA5223167	microsome format	Scientific Literature
2.	ALA5225739	A	Half life in ICR mouse at 1 mg/ml, iv measured for 24 hrs by HPLC analysis	Mus musculus	2	ALA5223167	organism-based format	Scientific Literature
3.	ALA5225740	A	Clearance in ICR mouse at 1 mg/ml, iv measured for 24 hrs by HPLC analysis	Mus musculus	2	ALA5223167	organism-based format	Scientific Literature
4.	ALA5225741	F	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by measuring fold improvement in IC50 incubated for 5 days by EZMTT assay relative to control	Homo sapiens	1	ALA5223167	cell-based format	Scientific Literature
5.	ALA5225742	F	Antiproliferative activity against mouse H22 cells assessed as inhibition of cell growth by measuring fold improvement in IC50 incubated for 5 days by EZMTT assay relative to control	Mus musculus	1	ALA5223167	cell-based format	Scientific Literature
6.	ALA5225743	F	Antiproliferative activity against human HCT-116 cells assessed as growth rate at 1 uM measured after 2 to 24 hrs by EZMTT assay (Rvb = 100%)	Homo sapiens	3	ALA5223167	cell-based format	Scientific Literature
7.	ALA5225744	F	Antiproliferative activity against human HCT-116 cells assessed as growth rate at 3 uM measured after 2 to 24 hrs by EZMTT assay (Rvb = 100%)	Homo sapiens	3	ALA5223167	cell-based format	Scientific Literature
8.	ALA5225745	F	Antiproliferative activity against human HCT-116 cells assessed as growth rate at 10 uM measured after 2 to 24 hrs by EZMTT assay (Rvb = 100%)	Homo sapiens	3	ALA5223167	cell-based format	Scientific Literature
9.	ALA5225746	F	Inhibition of colony formation in human A549 cells assessed as reduction in number and size of colonies incubated for 14 days by crystal violet staining based assay	Homo sapiens	2	ALA5223167	cell-based format	Scientific Literature
10.	ALA5225747	F	Induction of ROS production in human A549 cells at 5 to 10 uM incubated for 12 hrs by dichlorodihydro-fluorescein diacetate probe based fluorescence microscopic analysis	Homo sapiens	2	ALA5223167	cell-based format	Scientific Literature
11.	ALA5225748	B	Inhibition of human KGA using glutamine as substrate preincubated for 0.5 hrs followed by substrate addition and measured after 4 hrs by EZMTT reagent based assay	Homo sapiens	8	ALA5223167	single protein format	Scientific Literature
12.	ALA5225749	B	Inhibition of bovine GDH using glutamate as substrate preincubated for 0.5 hrs followed by substrate addition and further incubated for 1 hr in presence of NADP+ by EZMTT reagent based assay	Bos taurus	8	ALA5223167	single protein format	Scientific Literature
13.	ALA5225750	B	Binding affinity to alanine residue of human KGA K320A mutant assessed as covalent bond formation	Homo sapiens	2	ALA5223167	assay format	Scientific Literature
14.	ALA5225751	B	Covalent inhibition of wild type human KGA using glutamine as substrate at 10 uM preincubated for 0.5 hrs followed by substrate addition and measured after 4 hrs by EZMTT reagent based assay	Homo sapiens	2	ALA5223167	single protein format	Scientific Literature
15.	ALA5225752	B	Covalent inhibition of human KGA K320A mutant using glutamine as substrate at 10 uM preincubated for 0.5 hrs followed by substrate addition and measured after 4 hrs by EZMTT reagent based assay	Homo sapiens	2	ALA5223167	assay format	Scientific Literature
16.	ALA5225753	B	Inhibition of biotinylated N-[6-[4-[5-[[2-(2-pyridyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide binding to wild type human KGA at >300 nM by biomolecular interaction assay	Homo sapiens	2	ALA5223167	single protein format	Scientific Literature
17.	ALA5225754	B	Inhibition of biotinylated N-[6-[4-[5-[[2-(2-pyridyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide binding to human KGA K320A mutant by biomolecular interaction assay	Homo sapiens	2	ALA5223167	assay format	Scientific Literature
18.	ALA5225755	B	Binding affinity to wild type human KGA assessed as covalent bond formation by measuring dissociation constant by biomolecular interaction assay	Homo sapiens	3	ALA5223167	single protein format	Scientific Literature
19.	ALA5225756	B	Covalent binding affinity to Lys residue of wild type human KGA assessed as reduction in trypsin-mediated enzyme digestion at lys residue at 10 uM pretreated with compound followed by trypsin digestion by gel electrophoresis analysis relative to control	Homo sapiens	1	ALA5223167	single protein format	Scientific Literature
20.	ALA5225757	P	Stability of compound		7	ALA5223167	small-molecule physicochemical format	Scientific Literature