# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5230898 | B | Inhibition of human EGFR using 5-FAM-EEPLYWSFPAKKKCONH2 as substrate incubated for 30 mins in presence of ATP | Homo sapiens | 2 | ALA5230100 | single protein format | Scientific Literature | |
2. | ALA5230899 | B | Inhibition of human EGFR d746-750 mutant using 5-FAM-EEPLYWSFPAKKKCONH2 as substrate incubated for 30 mins in presence of ATP | Homo sapiens | 2 | ALA5230100 | single protein format | Scientific Literature | |
3. | ALA5230900 | B | Inhibition of human EGFR L858R mutant using 5-FAM-EEPLYWSFPAKKKCONH2 as substrate incubated for 30 mins in presence of ATP | Homo sapiens | 2 | ALA5230100 | single protein format | Scientific Literature | |
4. | ALA5230901 | B | Inhibition of human EGFR L858R/T790M mutant using 5-FAM-EEPLYWSFPAKKKCONH2 as substrate incubated for 30 mins in presence of ATP | Homo sapiens | 2 | ALA5230100 | single protein format | Scientific Literature | |
5. | ALA5230902 | F | Antiproliferative activity against human PC-9 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay | Homo sapiens | 2 | ALA5230100 | cell-based format | Scientific Literature | |
6. | ALA5230903 | F | Antiproliferative activity against human A-431 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay | Homo sapiens | 1 | ALA5230100 | cell-based format | Scientific Literature | |
7. | ALA5230904 | T | Permeability coefficient in human Caco-2 cells | Homo sapiens | 2 | ALA5230100 | cell-based format | Scientific Literature | |
8. | ALA5230905 | A | Half life in human liver microsomes by LC-MS/MS analysis | Homo sapiens | 2 | ALA5230100 | microsome format | Scientific Literature | |
9. | ALA5230906 | A | Clearance in Sprague-Dawley rat at 10 mg/kg, iv by LC/MS/MS analysis | Rattus norvegicus | 2 | ALA5230100 | organism-based format | Scientific Literature | |
10. | ALA5230907 | A | Volume of distribution at steady state in Sprague-Dawley rat at 10 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA5230100 | organism-based format | Scientific Literature | |
11. | ALA5230908 | A | AUClast in Sprague-Dawley rat plasma at 10 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA5230100 | organism-based format | Scientific Literature | |
12. | ALA5230909 | A | AUC (0 to infinity) in Sprague-Dawley rat plasma at 10 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA5230100 | organism-based format | Scientific Literature | |
13. | ALA5230910 | A | MRT (0 to 24 hrs) in Sprague-Dawley rat plasma at 10 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA5230100 | organism-based format | Scientific Literature | |
14. | ALA5230911 | A | Half life in Sprague-Dawley rat plasma at 10 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA5230100 | organism-based format | Scientific Literature |