# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5258489 | F | Induction of cell cycle arrest in human HT-29 cells assessed as accumulation of cells at G0/G1 phase at 1 uM incubated for 24 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 50.206%) | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
2. | ALA5258490 | F | Antiproliferative activity against human Caco-2 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 17 | ALA5257059 | cell-based format | Scientific Literature | |
3. | ALA5258491 | F | Antiproliferative activity against human DLD-1 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 17 | ALA5257059 | cell-based format | Scientific Literature | |
4. | ALA5258492 | F | Antiproliferative activity against human A-172 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 17 | ALA5257059 | cell-based format | Scientific Literature | |
5. | ALA5258493 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 17 | ALA5257059 | cell-based format | Scientific Literature | |
6. | ALA5258494 | F | Antiproliferative activity against human Tera-1 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 17 | ALA5257059 | cell-based format | Scientific Literature | |
7. | ALA5258495 | F | Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 18 | ALA5257059 | cell-based format | Scientific Literature | |
8. | ALA5258496 | F | Induction of cell cycle arrest in human HT-29 cells assessed as accumulation of cells at S phase at 1 uM incubated for 24 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 17.934 %) | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
9. | ALA5258497 | F | Induction of cell cycle arrest in human HT-29 cells assessed as accumulation of cells at G2/M phase at 1 uM incubated for 24 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 23.695 %) | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
10. | ALA5258498 | F | Induction of cell cycle arrest in human HT-29 cells assessed as accumulation of cells at subG1 phase at 1 uM incubated for 24 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 1.798%) | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
11. | ALA5258507 | F | Induction of mitochondrial damage in human HT-29 cells assessed as increase in monomer formation at 1 uM incubated for 24 hrs by JC-1 staining based flow cytometry analysis | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
12. | ALA5258510 | F | Induction of apoptosis in human HT29 cells assessed as increase in early apoptotic cells at 1 uM incubated for 24 hrs by annexin V/PI staining based flow cytometry analysis | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
13. | ALA5258513 | F | Induction of apoptosis in human HT29 cells assessed as increase in late apoptotic cells at 1 uM incubated for 24 hrs by annexin V/PI staining based flow cytometry analysis | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
14. | ALA5258516 | F | Induction of ROS generation in human HT-29 cells at 1 uM by CM-H2DCFDA fluorescent probe based flow cytometry analysis (Rvb = 0.528%) | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
15. | ALA5258519 | F | Induction of mitochondrial ROS generation in human HT-29 cells at 1 uM by MitoSOX red dye based flow cytometry analysis | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
16. | ALA5258522 | F | Downregulation of beta-catenin protein expression in human HT-29 cells at 1 uM by immunostaining based confocal microscopic analysis | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
17. | ALA5258525 | F | Downregulation of TAB-182 protein expression in human HT-29 cells at 1 uM by immunostaining based confocal microscopic analysis | Homo sapiens | 1 | ALA5257059 | cell-based format | Scientific Literature | |
18. | ALA5258528 | F | Downregulation of PI3K-p85 expression in human HT-29 cells by immunofluorescence based confocal microscopic analysis | Homo sapiens | 3 | ALA5257059 | cell-based format | Scientific Literature | |
19. | ALA5258529 | F | Inhibition of nuclear translocation of NFkappaB in human HT-29 cells assessed as reduction in NFkappaB expression in nucleus by immunofluorescence based confocal microscopic analysis | Homo sapiens | 3 | ALA5257059 | cell-based format | Scientific Literature | |
20. | ALA5258530 | F | Cytotoxicity against human HT-29 cells assessed as damage of actin filament by F-actin/phalloidin red staining based confocal microscopic analysis | Homo sapiens | 3 | ALA5257059 | cell-based format | Scientific Literature |