# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5242582 | B | Inhibition of human COX-1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by ELISA | Homo sapiens | 2 | ALA5241097 | single protein format | Scientific Literature | |
2. | ALA5242583 | B | Inhibition of recombinant human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by ELISA | Homo sapiens | 5 | ALA5241097 | single protein format | Scientific Literature | |
3. | ALA5242584 | B | Inhibition of potato 5-LOX using linoleic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by spectrophotometric assay | Solanum tuberosum | 1 | ALA5241097 | assay format | Scientific Literature | |
4. | ALA5242585 | B | Selectivity index, ratio of IC50 for inhibition of human COX1 to IC50 for inhibition of human COX2 | Homo sapiens | 7 | ALA5241097 | assay format | Scientific Literature | |
5. | ALA5242586 | F | Antiinflammatory activity in Wistar rat assessed as reduction in carragenan-induced paw edema at 10 mg/kg, po for 7 days followed by carrageenan stimulation and measured upto 6 hrs by vernier caliper method | Rattus norvegicus | 2 | ALA5241097 | organism-based format | Scientific Literature | |
6. | ALA5243072 | B | Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by ELISA | Homo sapiens | 100 | ALA5241111 | single protein format | Scientific Literature | |
7. | ALA5243073 | B | Inhibition of 5-LOX (unknown origin) using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by absorbance based analysis | Homo sapiens | 19 | ALA5241111 | single protein format | Scientific Literature | |
8. | ALA5243074 | B | Selectivity index, ratio of IC50 for inhibition of human COX-1 to IC50 for inhibition of human COX-2 | Homo sapiens | 74 | ALA5241111 | protein format | Scientific Literature |