# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5233155 | B | Irreversible inhibition of recombinant human TG2 expressed in Escherichia coli BL21 assessed as inhibition constant using AL5 as substrate by continuous chromogenic assay | Homo sapiens | 29 | assay format | Scientific Literature | ||
2. | ALA5233156 | B | Irreversible inhibition of recombinant human TG2 expressed in Escherichia coli BL21 assessed as Kinact using AL5 as substrate by continuous chromogenic assay | Homo sapiens | 29 | assay format | Scientific Literature | ||
3. | ALA5233157 | B | Irreversible inhibition of recombinant human TG2 expressed in Escherichia coli BL21 assessed as ratio of Kinact/Ki using AL5 as substrate by continuous chromogenic assay | Homo sapiens | 25 | assay format | Scientific Literature | ||
4. | ALA5233159 | A | Apparent permeability from apical to basolateral side in MDCK-MDR1 cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
5. | ALA5233160 | A | Apparent permeability from basolateral to apical side in MDCK-MDR1 cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
6. | ALA5233161 | A | Efflux ratio of apparent permeability in MDCK-MDR1 cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
7. | ALA5233162 | A | Apparent permeability from apical to basolateral side in MDCK-MDR1 cells in presence of Pgp inhibitor zosuquidar | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
8. | ALA5233163 | A | Apparent permeability from basolateral to apical side in MDCK-MDR1 cells in presence of Pgp inhibitor zosuquidar | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
9. | ALA5233164 | A | Efflux ratio of apparent permeability in MDCK-MDR1 cells in presence of Pgp inhibitor zosuquidar | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
10. | ALA5233165 | P | Lipophilicity, logP of the compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA5233166 | P | Permeability coefficient, logPe of the compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA5233167 | F | Antiproliferative activity against human SCC-13 cells assessed as dose-dependent inhibition at 25 to 100 uM incubated for 48 hrs by Coulter cell counter analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA5233168 | F | Inhibition of cell invasion in human SCC-13 cells at 10 to 50 uM measured over 20 hrs by DAPI staining based fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |