| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5265539 | Binding | Inhibition of PAK4 (unknown origin) | Homo sapiens | 3 | ALA5260856 | single protein format | Scientific Literature | |
| 2. | ALA5265540 | Binding | Inhibition of PLK4 (unknown origin) | Homo sapiens | 3 | ALA5260856 | single protein format | Scientific Literature | |
| 3. | ALA5265541 | Binding | Inhibition of FAK (unknown origin) | Homo sapiens | 3 | ALA5260856 | single protein format | Scientific Literature | |
| 4. | ALA5265542 | Binding | Inhibition of TRKC (unknown origin) using TK as substrate in presence of ATP incubated for 40 mins by HTRF KinEASE assay | Homo sapiens | 4 | ALA5260856 | single protein format | Scientific Literature | |
| 5. | ALA5265543 | Binding | Inhibition of TRKA (unknown origin) using TK as substrate in presence of ATP incubated for 30 mins by HTRF KinEASE assay | Homo sapiens | 39 | ALA5260856 | single protein format | Scientific Literature | |
| 6. | ALA5265545 | Binding | Inhibition of TRKB (unknown origin) using TK as substrate in presence of ATP incubated for 40 mins by HTRF KinEASE assay | Homo sapiens | 4 | ALA5260856 | single protein format | Scientific Literature | |
| 7. | ALA5265546 | ADME | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | microsome format | Scientific Literature | |
| 8. | ALA5265547 | ADME | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | microsome format | Scientific Literature | |
| 9. | ALA5265548 | ADME | Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | microsome format | Scientific Literature | |
| 10. | ALA5265549 | ADME | Stability in human plasma assessed as parent compound remaining at 100 uM and measured after 120 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | cell-free format | Scientific Literature | |
| 11. | ALA5265550 | ADME | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | microsome format | Scientific Literature | |
| 12. | ALA5265551 | ADME | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | microsome format | Scientific Literature | |
| 13. | ALA5265552 | ADME | Stability in human plasma assessed as parent compound remaining at 100 uM and measured after 60 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | cell-free format | Scientific Literature | |
| 14. | ALA5265553 | ADME | Stability in human plasma assessed as parent compound remaining at 100 uM and measured after 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | cell-free format | Scientific Literature | |
| 15. | ALA5265554 | ADME | Stability in human plasma assessed as parent compound remaining at 100 uM and measured after 10 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | cell-free format | Scientific Literature | |
| 16. | ALA5265555 | ADME | Stability in human plasma assessed as parent compound remaining at 100 uM and measured after 0 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | cell-free format | Scientific Literature | |
| 17. | ALA5265556 | ADME | Stability in human plasma assessed as half life at 100 uM and measured after 120 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA5260856 | cell-free format | Scientific Literature | |
| 18. | ALA5265557 | Toxicity | Cytotoxicity against human HUVEC cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay | Homo sapiens | 2 | ALA5260856 | cell-based format | Scientific Literature | |
| 19. | ALA5265558 | Functional | Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay | Homo sapiens | 2 | ALA5260856 | cell-based format | Scientific Literature | |
| 20. | ALA5265559 | Functional | Antiproliferative activity against human KM12 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay | Homo sapiens | 2 | ALA5260856 | cell-based format | Scientific Literature |
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