| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5240362 | B | Positive allosteric modulation of rat mGluR7 | Rattus norvegicus | 14 | ALA5236641 | single protein format | Scientific Literature | |
| 2. | ALA5240363 | B | Positive allosteric modulation of rat mGluR7 in presence of L-AP4 Max relative to control | Rattus norvegicus | 13 | ALA5236641 | single protein format | Scientific Literature | |
| 3. | ALA5240364 | A | Permeability coefficient of the compound | 3 | ALA5236641 | assay format | Scientific Literature | ||
| 4. | ALA5240365 | A | Unbound brain-to-plasma concentration ratio in rat | Rattus norvegicus | 3 | ALA5236641 | cell-free format | Scientific Literature | |
| 5. | ALA5240366 | B | Positive allosteric modulation of rat mGluR8 | Rattus norvegicus | 12 | ALA5236641 | assay format | Scientific Literature | |
| 6. | ALA5240368 | B | Positive allosteric modulation of human mGluR1 | Homo sapiens | 1 | ALA5236641 | single protein format | Scientific Literature | |
| 7. | ALA5240369 | B | Positive allosteric modulation of human mGluR2 | Homo sapiens | 1 | ALA5236641 | single protein format | Scientific Literature | |
| 8. | ALA5240370 | B | Positive allosteric modulation of human mGluR3 | Homo sapiens | 1 | ALA5236641 | single protein format | Scientific Literature | |
| 9. | ALA5240371 | B | Positive allosteric modulation of human mGluR4 | Homo sapiens | 1 | ALA5236641 | single protein format | Scientific Literature | |
| 10. | ALA5240372 | B | Positive allosteric modulation of human mGluR5 | Homo sapiens | 1 | ALA5236641 | single protein format | Scientific Literature | |
| 11. | ALA5240373 | B | Positive allosteric modulation of human mGluR8 | Homo sapiens | 1 | ALA5236641 | single protein format | Scientific Literature | |
| 12. | ALA5240374 | B | Inhibition of human sigma-1 receptor at 10 uM relative to control | Homo sapiens | 1 | ALA5236641 | single protein format | Scientific Literature | |
| 13. | ALA5240375 | A | Unbound fraction in rat plasma | Rattus norvegicus | 1 | ALA5236641 | cell-free format | Scientific Literature | |
| 14. | ALA5240376 | A | Unbound fraction in mouse plasma | Mus musculus | 1 | ALA5236641 | cell-free format | Scientific Literature | |
| 15. | ALA5240377 | A | Unbound fraction in rat brain | Rattus norvegicus | 1 | ALA5236641 | tissue-based format | Scientific Literature | |
| 16. | ALA5240378 | A | Unbound fraction in mouse brain | Mus musculus | 1 | ALA5236641 | tissue-based format | Scientific Literature | |
| 17. | ALA5240379 | A | Permeability coefficient in C57/BL6J wild type mouse at 30 mg/kg, ip measured after 30 mins | Mus musculus | 1 | ALA5236641 | organism-based format | Scientific Literature | |
| 18. | ALA5240380 | A | Permeability coefficient in C57/BL6J wild type mouse at 30 mg/kg, ip measured after 60 mins | Mus musculus | 1 | ALA5236641 | organism-based format | Scientific Literature | |
| 19. | ALA5240381 | A | Unbound brain to plasma concentration in C57/BL6J wild type mouse at 30 mg/kg, ip measured after 30 mins | Mus musculus | 1 | ALA5236641 | organism-based format | Scientific Literature | |
| 20. | ALA5240382 | A | Unbound brain to plasma concentration in C57/BL6J wild type mouse at 30 mg/kg, ip measured after 60 mins | Mus musculus | 1 | ALA5236641 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!