| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5242438 | B | Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis | Homo sapiens | 73 | ALA5241094 | cell-based format | Scientific Literature | |
| 2. | ALA5242441 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance measured per mg of protein | Mus musculus | 19 | ALA5241094 | microsome format | Scientific Literature | |
| 3. | ALA5242442 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance measured per mg of protein | Homo sapiens | 5 | ALA5241094 | microsome format | Scientific Literature | |
| 4. | ALA5242443 | P | Solubility of compound in PBS buffer at pH 7.4 and measured after 24 hrs | 5 | ALA5241094 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA5242444 | A | Efflux ratio of permeability in human Caco-2 cells | Homo sapiens | 5 | ALA5241094 | cell-based format | Scientific Literature | |
| 6. | ALA5242445 | A | Clearance in C57BL/6 mouse at 0.2 mg/kg, iv and measured after 2 hrs by HPLC-MS/MS analysis | Mus musculus | 8 | ALA5241094 | organism-based format | Scientific Literature | |
| 7. | ALA5242446 | A | Volume of distribution at steady state in C57BL/6 mouse at 0.2 mg/kg, iv and measured after 2 hrs by HPLC-MS/MS analysis | Mus musculus | 8 | ALA5241094 | organism-based format | Scientific Literature | |
| 8. | ALA5242453 | B | Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis | Homo sapiens | 5 | ALA5241094 | cell-based format | Scientific Literature | |
| 9. | ALA5242454 | B | Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis | Homo sapiens | 5 | ALA5241094 | cell-based format | Scientific Literature | |
| 10. | ALA5242455 | B | Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis | Homo sapiens | 6 | ALA5241094 | cell-based format | Scientific Literature |
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