# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5240686 | B | Inhibition of electric eel AChE using ATCI and BTCI as substrate preincubated for 5 mins followed by substrate addition and measured after 3 mins by DTNB-reagent based Ellman's method | Electrophorus electricus | 23 | single protein format | Scientific Literature | ||
2. | ALA5240687 | B | Inhibition of equine serum BuChE using ATCI and BTCI as substrate preincubated for 5 mins followed by substrate addition and measured after 3 mins by DTNB-reagent based Ellman's method | Equus caballus | 25 | cell-free format | Scientific Literature | ||
3. | ALA5240690 | B | Selectivity index, ratio of IC50 for inhibition of equine serum BuChE to IC50 for inhibition of electric eel AChE | 23 | assay format | Scientific Literature | |||
4. | ALA5240691 | F | Antioxidant activity assessed as trolox equivalent of ORAC radical scavenging activity by ORAC assay | 25 | assay format | Scientific Literature | |||
5. | ALA5240693 | B | Inhibition of human serum BuChE using ATCI and BTCI as substrate preincubated for 5 mins followed by substrate addition and measured after 3 mins by DTNB-reagent based Ellman's method | Homo sapiens | 15 | cell-free format | Scientific Literature | ||
6. | ALA5240694 | B | Inhibition of human erythrocyte AChE at 100 uM using ATCI and BTCI as substrate preincubated for 5 mins followed by substrate addition and measured after 3 mins by DTNB-reagent based Ellman's method relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA5240695 | B | Selectivity index, ratio of IC50 for inhibition of human erythrocyte AChE to IC50 for inhibition of human serum BuChE | 13 | assay format | Scientific Literature | |||
8. | ALA5240697 | A | Permeability coefficient of the compound across blood brain barrier incubated for 18 hrs by PAMPA assay | 25 | assay format | Scientific Literature |