# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5242438 | Binding | Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis | Homo sapiens | 73 | ALA5241094 | cell-based format | Scientific Literature | |
2. | ALA5242448 | Binding | Binding affinity to full-length C-terminal GFP-tagged human MCT4 assessed as equilibrium dissociation constant incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysis | Homo sapiens | 1 | ALA5241094 | single protein format | Scientific Literature | |
3. | ALA5242449 | Binding | Binding affinity to full-length C-terminal eGFP-tagged human MCT4 expressed in human HEK293 cell membranes at 10 uM incubated for 5 mins in presence of 0.5% Triton X by confocal microscopy | Homo sapiens | 2 | ALA5241094 | cell membrane format | Scientific Literature | |
4. | ALA5242450 | Binding | Binding affinity to full-length C-terminal eGFP-tagged human MCT4 expressed in human HEK293 cell membranes at 10 uM incubated for 5 mins by confocal microscopy | Homo sapiens | 1 | ALA5241094 | cell membrane format | Scientific Literature | |
5. | ALA5242451 | Binding | Binding affinity to full-length C-terminal GFP-tagged mouse MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysis | Mus musculus | 1 | ALA5241094 | cell membrane format | Scientific Literature | |
6. | ALA5242452 | Binding | Binding affinity to full-length C-terminal eGFP-tagged mouse MCT4 expressed in human HEK293 cell membranes at 10 uM incubated for 5 mins by confocal microscopy | Mus musculus | 1 | ALA5241094 | cell membrane format | Scientific Literature |