# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5230392 | F | Antiviral activity against HIV1 NL4-3 infected in human CEM-GFP cells assessed as inhibition in viral growth measured after 5 days by 96-well plate assay method | Homo sapiens | 1 | ALA5230085 | cell-based format | Scientific Literature | |
2. | ALA5230393 | B | Binding affinity to CXCR4 E288D mutant (unknown origin) by 12G5 competitive binding assay | Homo sapiens | 1 | ALA5230085 | single protein format | Scientific Literature | |
3. | ALA5230394 | F | Cytotoxicity against human CEM-GFP cells assessed as cell viability at 10 uM incubated for 5 days by Celltiter-blue assay method | Homo sapiens | 1 | ALA5230085 | cell-based format | Scientific Literature | |
4. | ALA5230395 | B | Binding affinity to CXCR4 (unknown origin) expressed in CHO cells incubated for 40 mins by competitive binding assay method | Homo sapiens | 19 | ALA5230085 | cell-based format | Scientific Literature | |
5. | ALA5230396 | B | Antagonist activity at CXCR4 receptor in SDF-1alpha-stimulated human SUP-T1 cells incubated for 30 mins by calcium mobilization assay | Homo sapiens | 2 | ALA5230085 | cell-based format | Scientific Literature | |
6. | ALA5230397 | B | Inhibition of SDF-1 alpha induced cell migration in human SUP-T1 cells pre-incubated for 30 mins followed by SDF-1 alpha addition measured after 3 hrs by cell Titer-96 reagent based analysis | Homo sapiens | 2 | ALA5230085 | cell-based format | Scientific Literature | |
7. | ALA5230398 | B | Binding affinity to CXCR4 (unknown origin) | Homo sapiens | 1 | ALA5230085 | single protein format | Scientific Literature | |
8. | ALA5230399 | B | Binding affinity to CXCR4 E288D mutant (unknown origin) by competitive binding assay method | Homo sapiens | 1 | ALA5230085 | single protein format | Scientific Literature | |
9. | ALA5230400 | B | Binding affinity to N-terminus CXCR4 D262A mutant (unknown origin) | Homo sapiens | 1 | ALA5230085 | single protein format | Scientific Literature | |
10. | ALA5230401 | B | Binding affinity to N-terminus CXCR4 R30A mutant (unknown origin) | Homo sapiens | 1 | ALA5230085 | single protein format | Scientific Literature | |
11. | ALA5230402 | B | Binding affinity to N-terminus CXCR4 H113A mutant (unknown origin) | Homo sapiens | 1 | ALA5230085 | single protein format | Scientific Literature | |
12. | ALA5230403 | B | Binding affinity to CXCR4 D193A mutant (unknown origin) assessed as reduction in potency | Homo sapiens | 1 | ALA5230085 | single protein format | Scientific Literature | |
13. | ALA5230404 | B | Binding affinity to CXCR4 W195A mutant (unknown origin) assessed as reduction in potency | Homo sapiens | 1 | ALA5230085 | single protein format | Scientific Literature |