# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5246637 | B | Inhibition of IRAK4 (unknown origin) in presence of ATP by enzymatic assay | Homo sapiens | 35 | single protein format | Scientific Literature | ||
2. | ALA5246638 | B | Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
3. | ALA5246639 | P | Lipophilicity, LogD at pH 7.4 of the compound by shake flask method | 35 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA5246640 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 27 | microsome format | Scientific Literature | ||
5. | ALA5246641 | A | Metabolic stability in human hepatocytes assessed as intrinsic clearance measured per 10^6 cells | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
6. | ALA5246644 | A | Metabolic stability in human cytosol assessed as intrinsic clearance | Homo sapiens | 8 | subcellular format | Scientific Literature | ||
7. | ALA5246678 | B | Inhibition of IRAK1 (unknown origin) in presence of 25 uM ATP | Homo sapiens | 3 | single protein format | Scientific Literature | ||
8. | ALA5246679 | B | Inhibition of BTK (unknown origin) in presence of 25 uM ATP | Homo sapiens | 3 | single protein format | Scientific Literature | ||
9. | ALA5246680 | B | Inhibition of FLT3 (unknown origin) in presence of 600 uM ATP | Homo sapiens | 6 | single protein format | Scientific Literature | ||
10. | ALA5246681 | B | Inhibition of PI3Kdelta (unknown origin) in presence of 75 uM ATP | Homo sapiens | 3 | single protein format | Scientific Literature | ||
11. | ALA5246682 | B | Inhibition of TRKA (unknown origin) in presence of 400 uM ATP | Homo sapiens | 4 | single protein format | Scientific Literature | ||
12. | ALA5246683 | B | Inhibition of TRKB (unknown origin) in presence of 25 uM ATP | Homo sapiens | 3 | single protein format | Scientific Literature | ||
13. | ALA5246684 | B | Inhibition of TRKC (unknown origin) in presence of 50 uM ATP | Homo sapiens | 3 | single protein format | Scientific Literature | ||
14. | ALA5246685 | B | Selectivity index, ratio of IC50 for inhibition of IRAK1 (unknown origin) to IC50 for inhibition of IRAK4 (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
15. | ALA5246686 | B | Selectivity index, ratio of IC50 for inhibition of BTK (unknown origin) to IC50 for inhibition of IRAK4 (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
16. | ALA5246687 | B | Selectivity index, ratio of IC50 for inhibition of FLT3 (unknown origin) to IC50 for inhibition of IRAK4 (unknown origin) | Homo sapiens | 5 | assay format | Scientific Literature | ||
17. | ALA5246688 | B | Selectivity index, ratio of IC50 for inhibition of PI3Kdelta (unknown origin) to IC50 for inhibition of IRAK4 (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
18. | ALA5246689 | B | Selectivity index, ratio of IC50 for inhibition of TRKA (unknown origin) to IC50 for inhibition of IRAK4 (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
19. | ALA5246690 | B | Selectivity index, ratio of IC50 for inhibition of TRKB (unknown origin) to IC50 for inhibition of IRAK4 (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature | ||
20. | ALA5246691 | B | Selectivity index, ratio of IC50 for inhibition of TRKC (unknown origin) to IC50 for inhibition of IRAK4 (unknown origin) | Homo sapiens | 3 | assay format | Scientific Literature |