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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5223843 B Partial agonist activity at human 5HT4E receptor expressed in CHO cells assessed as cAMP accumulation incubated for 4 hrs by luciferase reporter gene luminescence assay Homo sapiens 73 ALA5223084 cell-based format Scientific Literature 2. ALA5223844 B Partial agonist activity at human 5HT4E receptor expressed in CHO cells assessed as cAMP accumulation incubated for 4 hrs by luciferase reporter gene luminescence assay relative to control Homo sapiens 68 ALA5223084 cell-based format Scientific Literature 3. ALA5223845 A Drug metabolism in rat liver microsomes incubated for 30 mins in presence of NADPH by LC-MS/MS analysis Rattus norvegicus 26 ALA5223084 microsome format Scientific Literature 4. ALA5223846 A Drug metabolism in human liver microsomes incubated for 30 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 26 ALA5223084 microsome format Scientific Literature 5. ALA5223852 A Oral bioavailability in Wistar rat at 3 mg/kg measured for 24 hrs by LC-MS/MS analysis Rattus norvegicus 19 ALA5223084 organism-based format Scientific Literature 6. ALA5223853 A Cmax in Wistar rat at 3 mg/kg, po and 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis Rattus norvegicus 19 ALA5223084 organism-based format Scientific Literature 7. ALA5223854 A AUC in Wistar rat at 3 mg/kg, po and 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis Rattus norvegicus 19 ALA5223084 organism-based format Scientific Literature 8. ALA5223855 A Elimination half life in Wistar rat at 3 mg/kg, po and 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis Rattus norvegicus 19 ALA5223084 organism-based format Scientific Literature 9. ALA5223856 A Volume of distribution at steady state in Wistar rat at 3 mg/kg, po and 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis Rattus norvegicus 19 ALA5223084 organism-based format Scientific Literature 10. ALA5223857 A Clearance in Wistar rat at 1 mg/kg, iv measured for 24 hrs by LC-MS/MS analysis Rattus norvegicus 19 ALA5223084 organism-based format Scientific Literature 11. ALA5223858 A Ratio of drug level in Wistar rat brain to plasma at 10 mg/kg, po measured after 1 hr by LC-MS/MS analysis Rattus norvegicus 19 ALA5223084 organism-based format Scientific Literature