# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5232960 | B | Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione [1beta-3H] as substrate incubated for 1 hrs by scintillation counting analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
2. | ALA5232961 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell growth at 1 uM incubated for 48 hrs by BrdU cell proliferation assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
3. | ALA5232962 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell growth at 1 uM incubated for 48 hrs by BrdU cell proliferation assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
4. | ALA5232963 | T | Cytotoxicity against human MCF-10A cells assessed as reduction in cell growth at 1 uM incubated for 48 hrs by BrdU cell proliferation assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
5. | ALA5232964 | A | Inhibition of CYP1A2 in human liver microsomes using ethoxyresorufin as substrate | Homo sapiens | 2 | microsome format | Scientific Literature | ||
6. | ALA5232965 | A | Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
7. | ALA5232966 | A | Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
8. | ALA5232967 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
9. | ALA5232968 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam/testosterone as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
10. | ALA5232969 | B | Selectivity index, ratio of IC50 for inhibition of CYP1A2 in human liver microsomes to IC50 for inhibition of CYP19A1 in human JEG-3 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5232970 | B | Selectivity index, ratio of IC50 for inhibition of CYP2C9 in human liver microsomes to IC50 for inhibition of CYP19A1 in human JEG-3 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5232971 | B | Selectivity index, ratio of IC50 for inhibition of CYP2C19 in human liver microsomes to IC50 for inhibition of CYP19A1 in human JEG-3 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA5232972 | B | Selectivity index, ratio of IC50 for inhibition of CYP2D6 in human liver microsomes to IC50 for inhibition of CYP19A1 in human JEG-3 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA5232973 | B | Selectivity index, ratio of IC50 for inhibition of CYP3A4 in human liver microsomes to IC50 for inhibition of CYP19A1 in human JEG-3 cells | Homo sapiens | 1 | cell-based format | Scientific Literature |