| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5252012 | B | Inhibition of N-terminal 6-His tagged human recombinant GSK3-beta H355L mutant using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrs | Homo sapiens | 32 | ALA5247659 | assay format | Scientific Literature | |
| 2. | ALA5252013 | B | Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrs | Homo sapiens | 32 | ALA5247659 | single protein format | Scientific Literature | |
| 3. | ALA5252023 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins by LC-MS/MS analysis | Homo sapiens | 6 | ALA5247659 | microsome format | Scientific Literature | |
| 4. | ALA5252024 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins by LC-MS/MS analysis | Mus musculus | 6 | ALA5247659 | microsome format | Scientific Literature | |
| 5. | ALA5252027 | A | Plasma protein binding in mouse assessed as unbound fraction at 10 uM measured for 5 hrs by equilibrium dialysis based LC-MS/MS analysis | Mus musculus | 6 | ALA5247659 | cell-free format | Scientific Literature | |
| 6. | ALA5252028 | A | Plasma protein binding in human assessed as unbound fraction at 10 uM measured for 5 hrs by equilibrium dialysis based LC-MS/MS analysis | Homo sapiens | 6 | ALA5247659 | cell-free format | Scientific Literature | |
| 7. | ALA5252029 | A | Permeability of compound at pH 5.5 incubated for 4 hrs by PAMPA assay | 6 | ALA5247659 | assay format | Scientific Literature | ||
| 8. | ALA5252030 | A | Permeability of compound at pH 7.4 incubated for 4 hrs by PAMPA assay | 6 | ALA5247659 | assay format | Scientific Literature | ||
| 9. | ALA5252031 | A | Permeability across apical to basolateral side in human Caco-2 cells at 3 uM incubated for 2 hrs by LC-MS/MS analysis | Homo sapiens | 6 | ALA5247659 | cell-based format | Scientific Literature | |
| 10. | ALA5252032 | A | Permeability across basolateral to apical side in human Caco-2 cells at 3 uM incubated for 2 hrs by LC-MS/MS analysis | Homo sapiens | 6 | ALA5247659 | cell-based format | Scientific Literature |
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