# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5243881 | P | 1-Octanol/aqueous buffer partition coefficient, logD of the compound at pH 7.4 by chromatographic method based UV-visible detector | 18 | ALA5241126 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA5243882 | B | Positive allosteric modulator activity at GluN2A NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glutamate and glycine by Ca2+ influx assay | Homo sapiens | 18 | ALA5241126 | cell-based format | Scientific Literature | |
3. | ALA5243883 | B | Positive allosteric modulator activity at GluN2A NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a assessed as maximum potentiation at 30 uM in the presence of L-glutamate and glycine by Ca2+ influx assay relative to control | Homo sapiens | 18 | ALA5241126 | cell-based format | Scientific Literature | |
4. | ALA5243884 | B | Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assay | Homo sapiens | 17 | ALA5241126 | single protein format | Scientific Literature | |
5. | ALA5243885 | A | Metabolic stability in human liver microsomes assessed as clearance at 1 uM incubated for 15 to 30 mins in the presence of NADPH generating system by LC-MS/MS analysis | Homo sapiens | 8 | ALA5241126 | microsome format | Scientific Literature | |
6. | ALA5243886 | A | Metabolic stability in rat liver microsomes assessed as clearance at 1 uM incubated for 15 to 30 mins in the presence of NADPH generating system by LC-MS/MS analysis | Rattus norvegicus | 8 | ALA5241126 | microsome format | Scientific Literature |