# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5223986 | F | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as reduction in bacterial growth incubated for 16 to 18 hrs by microdilution susceptibility test | Staphylococcus aureus | 18 | ALA5223087 | organism-based format | Scientific Literature | |
2. | ALA5223987 | F | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 assessed as reduction in bacterial growth incubated for 16 to 18 hrs by microdilution susceptibility test | Staphylococcus epidermidis | 18 | ALA5223087 | organism-based format | Scientific Literature | |
3. | ALA5223988 | F | Antimicrobial activity against Bacillus megaterium Bm11 assessed as reduction in bacterial growth incubated for 16 to 18 hrs by microdilution susceptibility test | Priestia megaterium | 18 | ALA5223087 | organism-based format | Scientific Literature | |
4. | ALA5223989 | F | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as reduction in bacterial growth incubated for 16 to 18 hrs by microdilution susceptibility test | Escherichia coli | 18 | ALA5223087 | organism-based format | Scientific Literature | |
5. | ALA5223990 | F | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 assessed as reduction in bacterial growth incubated for 16 to 18 hrs by microdilution susceptibility test | Pseudomonas aeruginosa | 18 | ALA5223087 | organism-based format | Scientific Literature | |
6. | ALA5223991 | F | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 assessed as reduction in bacterial growth incubated for 16 to 18 hrs by microdilution susceptibility test | Acinetobacter baumannii | 18 | ALA5223087 | organism-based format | Scientific Literature | |
7. | ALA5223992 | T | Cytotoxicity against human HaCaT cells assessed as reduction in cell viability at 25 uM measured after 2 hrs by MTT assay | Homo sapiens | 2 | ALA5223087 | cell-based format | Scientific Literature | |
8. | ALA5223993 | T | Cytotoxicity against human HaCaT cells assessed as reduction in cell viability at 50 uM measured after 2 hrs by MTT assay | Homo sapiens | 2 | ALA5223087 | cell-based format | Scientific Literature | |
9. | ALA5223994 | T | Cytotoxicity against human HaCaT cells assessed as reduction in cell viability at 50 uM measured after 24 hrs by MTT assay | Homo sapiens | 2 | ALA5223087 | cell-based format | Scientific Literature | |
10. | ALA5224011 | B | Membrano-lytic effect in bacterial inner membrane mimic DOPG/CL (58:42) large unilamellar vesicles at 50 uM by varian cary eclipse fluorescence spectrometry analysis | 1 | ALA5223087 | cell membrane format | Scientific Literature | ||
11. | ALA5224012 | B | Membrano-lytic effect in bacterial inner membrane mimic DOPE/DOPG/CL (63:23:12) large unilamellar vesicles at 5 to 50 uM by varian cary eclipse fluorescence spectrometry analysis | 3 | ALA5223087 | cell membrane format | Scientific Literature | ||
12. | ALA5224013 | B | Membrano-lytic effect in bacterial inner membrane mimic DOPE/DOPG/CL (63:23:12) large unilamellar vesicles at 10 uM by varian cary eclipse fluorescence spectrometry analysis | 3 | ALA5223087 | cell membrane format | Scientific Literature | ||
13. | ALA5224014 | B | Membrano-lytic effect in bacterial inner membrane mimic DOPG/CL (58:42) large unilamellar vesicles assessed as ratio of the ellipticities at 222 and 208 nM by varian cary eclipse fluorescence spectrometry analysis | 3 | ALA5223087 | cell membrane format | Scientific Literature | ||
14. | ALA5224015 | B | Membrano-lytic effect in bacterial inner membrane mimic DOPE/DOPG/CL (63:23:12) large unilamellar vesicles assessed as ratio of the ellipticities at 222 and 208 nM by varian cary eclipse fluorescence spectrometry analysis | 3 | ALA5223087 | cell membrane format | Scientific Literature | ||
15. | ALA5224016 | P | Disaggregation property of compound in LPS at 20 uM after 1 hr by Tht fluorescence based assay | 3 | ALA5223087 | small-molecule physicochemical format | Scientific Literature |