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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5256717 B Agonist activity at human GPR52 expressed in HEK293F assessed as cAMP accumulation preincubated for 30 mins followed by cAMP detection reagent and measured after 1 hr by HTRF analysis Homo sapiens 17 cell-based format Scientific Literature 2. ALA5256718 A Metabolic stability in rat liver microsomes assessed as intrinsic clearance preincubation with compound followed by NADPH addition and measured after 45 mins by LC-MS/MS analysis Rattus norvegicus 17 microsome format Scientific Literature 3. ALA5256719 A Metabolic stability in human liver microsomes assessed as intrinsic clearance preincubation with compound followed by NADPH addition and measured after 45 mins by LC-MS/MS analysis Homo sapiens 17 microsome format Scientific Literature 4. ALA5256720 A Apparent permeability of compound across apical to basolateral side in dog MDCK-MDR1 cells incubated for 1 hr by LC-MS/MS analysis Canis lupus familiaris 17 cell-based format Scientific Literature 5. ALA5256721 A Substrate activity at P-gp in dog MDCK-MDR1 cells assessed as efflux ratio incubated for 1 hr by LC-MS/MS analysis Canis lupus familiaris 17 cell-based format Scientific Literature 6. ALA5256722 P Kinetic solubility of compound at pH 7.4 at 1 to 100 uM incubated for 2 hrs by UV-visible spectroscopy analysis 17 small-molecule physicochemical format Scientific Literature 7. ALA5256723 P Octanol-water partition coefficient, log D of the compound by chromatographic method 17 small-molecule physicochemical format Scientific Literature 8. ALA5256724 P Lipophilicity, logP of the compound by shake flask assay 3 small-molecule physicochemical format Scientific Literature 9. ALA5256725 A Clearance in Sprague-Dawley rat plasma at 1 mg/kg,iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 10. ALA5256726 A Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg,iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 11. ALA5256727 A Half life in Sprague-Dawley rat at 1 mg/kg,iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 12. ALA5256728 A AUC (0 to infinity) in Sprague-Dawley rat at 1 mg/kg,iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 13. ALA5256729 A Fraction unbound in Sprague-Dawley rat plasma at 1 mg/kg,iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 14. ALA5256730 A Unbound brain-to-plasma concentration ratio in Sprague-Dawley rat plasma at 1 mg/kg,iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 15. ALA5256731 A AUC (0 to infinity) in Sprague-Dawley rat at 3 mg/kg,po by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 16. ALA5256732 A Cmax in Sprague-Dawley rat at 3 mg/kg,po by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 17. ALA5256733 A Oral bioavailability in Sprague-Dawley rat at 3 mg/kg by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 18. ALA5256734 A Oral absorption in Sprague-Dawley rat at 3 mg/kg by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 19. ALA5256735 A Clearance in CD-1 mouse plasma at 1 mg/kg,iv by LC-MS/MS analysis Mus musculus 1 organism-based format Scientific Literature 20. ALA5256736 A Volume of distribution at steady state in CD-1 mouse at 1 mg/kg,iv by LC-MS/MS analysis Mus musculus 1 organism-based format Scientific Literature