| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5225647 | B | Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 3 hrs without shaking by resorufin dye based fluorescence analysis | Homo sapiens | 34 | ALA5223163 | single protein format | Scientific Literature | |
| 2. | ALA5225648 | B | Inhibition of His-tagged human recombinant full length ME2 using L-malate and beta-NAD+ as substrate preincubated with enzyme for 5 mins followed by beta-NAD+ challenge and incubated under shaking for 5 mins followed by incubation for 2 hrs without shaking by resorufin dye based fluorescence analysis | Homo sapiens | 32 | ALA5223163 | single protein format | Scientific Literature | |
| 3. | ALA5225649 | B | Inhibition of His-tagged human recombinant full length ME1 using L-malate and beta-NADP+ as substrate preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 2 hrs without shaking by resorufin dye based fluorescence analysis | Homo sapiens | 32 | ALA5223163 | single protein format | Scientific Literature | |
| 4. | ALA5225650 | F | Antiproliferative activity against SMAD4/ME2-null human BXPC-3 cells assessed as inhibition of cell growth at 10 uM incubated for 72 hrs by CellTiter-Glo luminescence assay | Homo sapiens | 31 | ALA5223163 | cell-based format | Scientific Literature | |
| 5. | ALA5225651 | F | Antiproliferative activity against SMAD4/ME2-null human BXPC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by CellTiter-Glo luminescence assay | Homo sapiens | 14 | ALA5223163 | cell-based format | Scientific Literature | |
| 6. | ALA5225652 | B | Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate at 1 uM preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 3 hrs without shaking by resorufin dye based fluorescence analysis | Homo sapiens | 16 | ALA5223163 | single protein format | Scientific Literature | |
| 7. | ALA5225653 | B | Inhibition of His-tagged human recombinant ME3 (26 to 604 residues) using L-malate and beta-NADP+ as substrate at 10 uM preincubated with enzyme for 5 mins followed by beta-NADP+ challenge and incubated under shaking for 5 mins followed by incubation for 3 hrs without shaking by resorufin dye based fluorescence analysis | Homo sapiens | 11 | ALA5223163 | single protein format | Scientific Literature | |
| 8. | ALA5225665 | U | Selectivity for SMAD4/ME2-null human BXPC-3 cells over human HCE-T cells | 24 | ALA5223163 | assay format | Scientific Literature |
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