# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5228272 | B | Inhibition of TNKS1 (unknown origin) using biotinylated NAD as substrate assessed as inhibition of autoPARsylation activity incubated for 1 hr by ELISA | Homo sapiens | 24 | ALA5226325 | single protein format | Scientific Literature | |
2. | ALA5228273 | B | Modulation of Wnt/beta-catenin signaling pathway in human DLD-1 cells assessed as induction of AXIN2 accumulation incubated for 24 hrs by ELISA | Homo sapiens | 24 | ALA5226325 | cell-based format | Scientific Literature | |
3. | ALA5228274 | P | Solubility of compound at pH 7.4 | 24 | ALA5226325 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5228276 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance per mg of protein by UPLC analysis | Homo sapiens | 23 | ALA5226325 | microsome format | Scientific Literature | |
5. | ALA5228277 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance per mg of protein by UPLC analysis | Mus musculus | 24 | ALA5226325 | microsome format | Scientific Literature | |
6. | ALA5228278 | B | Inhibition of TNKS2 (unknown origin) using biotinylated NAD as substrate assessed as inhibition of autoPARsylation activity incubated for 1 hr by ELISA | Homo sapiens | 23 | ALA5226325 | single protein format | Scientific Literature | |
7. | ALA5228279 | B | Inhibition of PARP-1 (unknown origin) using biotinylated NAD and NAD as substrate assessed as inhibition of auto-PARsylation incubated for 150 mins by TR-FRET assay | Homo sapiens | 23 | ALA5226325 | single protein format | Scientific Literature | |
8. | ALA5228280 | P | Lipophilicity, logD of compound at pH 7.4 | 12 | ALA5226325 | small-molecule physicochemical format | Scientific Literature |