# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5248708 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as ALP activity at 0.001 to 100 uM measured for 24 to 48 hrs | Mus musculus | 32 | ALA5247581 | cell-based format | Scientific Literature | |
2. | ALA5248709 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as fold increase in BMP2 gene expression at 100 pM by qRT-PCR analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
3. | ALA5248710 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as ALP activity by measuring maximum efficacy at 0.001 to 100 uM measured for 24 to 48 hrs relative to control | Mus musculus | 28 | ALA5247581 | cell-based format | Scientific Literature | |
4. | ALA5248711 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as ALP activity at 0.001 to 100 uM measured for 48 hrs | Mus musculus | 4 | ALA5247581 | cell-based format | Scientific Literature | |
5. | ALA5248712 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as ALP activity at 0.001 to 100 uM measured for 24 hrs | Mus musculus | 4 | ALA5247581 | cell-based format | Scientific Literature | |
6. | ALA5248715 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as ALP activity at 0.001 to 1 uM measured for 48 hrs | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
7. | ALA5248716 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as ALP activity at 100 pM measured for 24 to 48 hrs | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
8. | ALA5248720 | Toxicity | Cytotoxicity against mouse Osteoblast cells assessed as reduction in cell viability at 0.000001 to 1 uM measured for 24 to 48 hrs by MTT assay | Mus musculus | 4 | ALA5247581 | cell-based format | Scientific Literature | |
9. | ALA5248721 | Toxicity | Cytotoxicity against mouse Osteoblast cells assessed as reduction in cell viability at 100 uM measured for 24 to 48 hrs by MTT assay | Mus musculus | 4 | ALA5247581 | cell-based format | Scientific Literature | |
10. | ALA5248722 | Functional | Induction of osteoblast differentiation in mouse calvarial osteoblasts cells assessed as ALP activity at 1 to 10000 pM measured for 7 days | Mus musculus | 3 | ALA5247581 | cell-based format | Scientific Literature | |
11. | ALA5248724 | Functional | Induction of osteoblast mineralization in mouse Bone marrow cells assessed as increase in mineralized nodule formation at 10 nM replaced with media every 48 hrs for 21 days by Alizarin Red staining-based microscopic analysis | Mus musculus | 2 | ALA5247581 | cell-based format | Scientific Literature | |
12. | ALA5248725 | Functional | Induction of osteoblast mineralization in mouse Bone marrow cells assessed as increase in mineralized nodule formation at 100 pM replaced with media every 48 hrs for 21 days by Alizarin Red staining-based microscopic analysis | Mus musculus | 2 | ALA5247581 | cell-based format | Scientific Literature | |
13. | ALA5248726 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as fold increase in RUNX2 gene expression at 1 pM by qRT-PCR analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
14. | ALA5248728 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as fold increase in mRNA expression at 1 to 10000 pM by qRT-PCR analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
15. | ALA5248729 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as fold increase in ALP expression at 100 pM by qRT-PCR analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
16. | ALA5248730 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as fold increase in BGLAP expression at 1 to 100 pM by qRT-PCR analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
17. | ALA5248731 | Functional | Induction of osteogenesis in mouse Osteoblast cells assessed as fold increase in BGLAP expression at 10 nM by qRT-PCR analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
18. | ALA5248732 | Functional | Induction of osteoblast differentiation in mouse Osteoblast cells assessed as fold increase in RUNX2 expression at 100 pM by qRT-PCR analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
19. | ALA5248733 | Functional | Induction of osteoblast differentiation in mouse Osteoblast cells assessed as fold increase in BMP2 expression at 100 pM by qRT-PCR analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature | |
20. | ALA5248734 | Functional | Upregulation of BMP2 expression in mouse Osteoblast cells assessed as fold increase in phosphorylated p38 level measured at 24 hrs by ELISA analysis | Mus musculus | 1 | ALA5247581 | cell-based format | Scientific Literature |