# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA651283 | F | Cytotoxicity against human breast cancer cells. | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
2. | ALA651284 | F | In vitro cytotoxicity against Plasmodium falciparum infected BC cell line. | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
3. | ALA668062 | B | Cytotoxicity by selective inhibition against human dihydrofolate reductase (DHFR);NA is no inhibition | 3 | single protein format | Scientific Literature | |||
4. | ALA663728 | B | Binding affinity towards mutant dihydrofolate reductase (C59R+S108N+I164L DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
5. | ALA667200 | B | Binding affinity towards mutant dihydrofolate reductase (N51I+C59R+S108N DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
6. | ALA880697 | B | Binding affinity towards mutant dihydrofolate reductase (N51I+C59R+S108N+I164L DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
7. | ALA668409 | B | Inhibition of the C59R+S108N mutant of dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
8. | ALA668410 | B | Inhibition of the S108N mutant of dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
9. | ALA668411 | B | Inhibition of the wild-type dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
10. | ALA668419 | B | Inhibition of the C59R+S108N mutant of dihydrofolate reductase (DHFR)relative to Pyr | Plasmodium falciparum | 8 | single protein format | Scientific Literature | ||
11. | ALA667457 | B | Inhibition of the S108N mutant of dihydrofolate reductase (DHFR)relative to Pyr | Plasmodium falciparum | 8 | single protein format | Scientific Literature | ||
12. | ALA667611 | B | Inhibition of Plasmodium falciparum wild-type dihydrofolate reductase (DHFR) relative to Pyrimethamine. | Plasmodium falciparum | 21 | single protein format | Scientific Literature | ||
13. | ALA701605 | F | Cytotoxicity against human epidermoid carcinoma KB cell. | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
14. | ALA704856 | F | In vitro cytotoxicity against Plasmodium falciparum infected KB cell line | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
15. | ALA762995 | F | Antiplasmodial activity IC50 against Plasmodium falciparum K1CB1 DHFR double-mutant (C59R/S10) | Plasmodium falciparum | 43 | assay format | Scientific Literature | ||
16. | ALA767132 | F | In vitro antiplasmodial activity (IC50) against Plasmodium falciparum wtTM4/8.2 | Plasmodium falciparum | 43 | organism-based format | Scientific Literature | ||
17. | ALA760860 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase C59R+S108N/I164L (Csl-2) mutant | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
18. | ALA765484 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase CN51I/C59R/S108N/I164L (V1/S) mutant | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
19. | ALA765485 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase N51I/C59R/S108N (W2) | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
20. | ALA765486 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase wild type (TM4/8.2) | Plasmodium falciparum | 28 | assay format | Scientific Literature |