# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5260478 | Binding | Inhibition of human recombinant full-length MEK7 using JNK1 as substrate incubated for 30 mins followed by ATP addition measured after 1 hr by ADP Glo luminescent assay | Homo sapiens | 33 | ALA5257149 | single protein format | Scientific Literature | |
2. | ALA5260479 | Binding | Inhibition of human recombinant full-length MEK4 using p38-alpha as substrate incubated for 30 mins followed by ATP addition measured after 1 hr by ADP Glo luminescent assay | Homo sapiens | 3 | ALA5257149 | single protein format | Scientific Literature | |
3. | ALA5260480 | Binding | Selectivity ratio, ratio of IC50 for human MEK4 to IC50 for human MEK7 by ADP Glo luminescent assay | Homo sapiens | 3 | ALA5257149 | assay format | Scientific Literature | |
4. | ALA5260481 | Binding | Inhibition of MEK3 (unknown origin) | Homo sapiens | 3 | ALA5257149 | single protein format | Scientific Literature | |
5. | ALA5260482 | Binding | Inhibition of MEK5 (unknown origin) | Homo sapiens | 3 | ALA5257149 | single protein format | Scientific Literature | |
6. | ALA5260483 | Binding | Inhibition of MEK6 (unknown origin) | Homo sapiens | 3 | ALA5257149 | single protein format | Scientific Literature | |
7. | ALA5260484 | Functional | Cytotoxicity against human RPMI 8402 cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | ALA5257149 | cell-based format | Scientific Literature | |
8. | ALA5260485 | Functional | Cytotoxicity against human KOPT-K1 cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | ALA5257149 | cell-based format | Scientific Literature | |
9. | ALA5260486 | Functional | Cytotoxicity against human ALL-SIL cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | ALA5257149 | cell-based format | Scientific Literature | |
10. | ALA5260487 | Functional | Cytotoxicity against human Jurkat cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | ALA5257149 | cell-based format | Scientific Literature | |
11. | ALA5260488 | Binding | Inhibition of MEK3 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
12. | ALA5260489 | Binding | Inhibition of MEK5 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
13. | ALA5260490 | Binding | Inhibition of MEK6 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
14. | ALA5260491 | Binding | Inhibition of MEK1 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
15. | ALA5260492 | Binding | Inhibition of MEK2 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
16. | ALA5260493 | Binding | Inhibition of p38alphaMAPK (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
17. | ALA5260494 | Binding | Inhibition of p38betaMAPK (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
18. | ALA5260495 | Binding | Inhibition of JNK1 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
19. | ALA5260496 | Binding | Inhibition of JNK2 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature | |
20. | ALA5260497 | Binding | Inhibition of JNK3 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | ALA5257149 | single protein format | Scientific Literature |