# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5260478 | B | Inhibition of human recombinant full-length MEK7 using JNK1 as substrate incubated for 30 mins followed by ATP addition measured after 1 hr by ADP Glo luminescent assay | Homo sapiens | 33 | single protein format | Scientific Literature | ||
2. | ALA5260479 | B | Inhibition of human recombinant full-length MEK4 using p38-alpha as substrate incubated for 30 mins followed by ATP addition measured after 1 hr by ADP Glo luminescent assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
3. | ALA5260480 | B | Selectivity ratio, ratio of IC50 for human MEK4 to IC50 for human MEK7 by ADP Glo luminescent assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
4. | ALA5260481 | B | Inhibition of MEK3 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
5. | ALA5260482 | B | Inhibition of MEK5 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
6. | ALA5260483 | B | Inhibition of MEK6 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
7. | ALA5260484 | F | Cytotoxicity against human RPMI 8402 cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA5260485 | F | Cytotoxicity against human KOPT-K1 cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA5260486 | F | Cytotoxicity against human ALL-SIL cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA5260487 | F | Cytotoxicity against human Jurkat cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA5260488 | B | Inhibition of MEK3 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA5260489 | B | Inhibition of MEK5 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA5260490 | B | Inhibition of MEK6 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA5260491 | B | Inhibition of MEK1 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA5260492 | B | Inhibition of MEK2 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA5260493 | B | Inhibition of p38alphaMAPK (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA5260494 | B | Inhibition of p38betaMAPK (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA5260495 | B | Inhibition of JNK1 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA5260496 | B | Inhibition of JNK2 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA5260497 | B | Inhibition of JNK3 (unknown origin) by discoverX kinomescan assay | Homo sapiens | 1 | single protein format | Scientific Literature |