# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5248749 | Binding | Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid scintillation counting analysis | Homo sapiens | 33 | ALA5247582 | cell-based format | Scientific Literature | |
2. | ALA5248750 | Functional | Anti-hyperuricemic activity against hypoxanthine/potassium oxonate-induced Kunming mouse model assessed as reduction in serum uric acid level at 2 mg/kg, sc measured after 4 hrs (Rvb = 1010.00 +/- 51.16 uM) | Mus musculus | 11 | ALA5247582 | organism-based format | Scientific Literature | |
3. | ALA5248751 | Functional | Anti-hyperuricemic activity against hypoxanthine/potassium oxonate-induced Kunming mouse model assessed as decrease in serum uric acid ratio at 2 mg/kg, sc measured after 4 hrs | Mus musculus | 11 | ALA5247582 | organism-based format | Scientific Literature | |
4. | ALA5248753 | Binding | Inhibition of GLUT9 (unknown origin) transfected in HEK293 cells assessed as inhibition of uric acid-induced current by whole cell patch clamp analysis | Homo sapiens | 1 | ALA5247582 | cell-based format | Scientific Literature | |
5. | ALA5248754 | Toxicity | Acute toxicity in Kunming male mouse assessed as survival rate at 1000 mg/kg, IG | Mus musculus | 2 | ALA5247582 | organism-based format | Scientific Literature | |
6. | ALA5248755 | Toxicity | Acute toxicity in Kunming female mouse assessed as survival rate at 1000 mg/kg, IG | Mus musculus | 2 | ALA5247582 | organism-based format | Scientific Literature | |
7. | ALA5248756 | Toxicity | Acute toxicity in Kunming female mouse assessed as lethargy at 1000 mg/kg, IG | Mus musculus | 1 | ALA5247582 | organism-based format | Scientific Literature | |
8. | ALA5248757 | Toxicity | Acute toxicity in Kunming female mouse assessed as clonic convulsion at 1000 mg/kg, IG | Mus musculus | 1 | ALA5247582 | organism-based format | Scientific Literature | |
9. | ALA5248758 | Toxicity | Acute toxicity in Kunming female mouse assessed as anorexia at 1000 mg/kg, IG | Mus musculus | 1 | ALA5247582 | organism-based format | Scientific Literature | |
10. | ALA5248759 | Toxicity | Acute toxicity in Kunming female mouse assessed as ruffled fur at 1000 mg/kg, IG | Mus musculus | 1 | ALA5247582 | organism-based format | Scientific Literature | |
11. | ALA5248760 | Toxicity | Acute toxicity in Kunming female mouse assessed as effect on body weight changes at 1000 mg/kg, IG measured for 7 days | Mus musculus | 1 | ALA5247582 | organism-based format | Scientific Literature |