| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5225830 | B | Inhibition of HPK1 in human Jurkat cells assessed as inhibition constant incubated for 1 hr by HTRF assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 2. | ALA5225831 | B | Inhibition of HPK1 in human Jurkat cells assessed as inhibition of SLP76 phosphorylation by measuring inhibition constant incubated for 1 hr by HTRF assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 3. | ALA5225832 | B | Inhibition of TRKA (unknown origin) incubated for 90 mins in presence of ATP by microplate reader assay | Homo sapiens | 30 | single protein format | Scientific Literature | ||
| 4. | ALA5225837 | B | Inhibition of MAP4K2 (unknown origin) incubated for 90 mins in presence of ATP by microplate reader assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 5. | ALA5225838 | B | Inhibition of STK4 (unknown origin) incubated for 90 mins in presence of ATP by microplate reader assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 6. | ALA5225840 | B | Inhibition of human HPK1 in human whole blood assessed as reduction in SLP76 phosphorylation incubated for 1 hr by HTRF assay | Homo sapiens | 10 | tissue-based format | Scientific Literature | ||
| 7. | ALA5225841 | T | Inhibition of hERG at 30 uM incubated for 24 hrs by scintillation counter analysis relative to control | Homo sapiens | 11 | assay format | Scientific Literature | ||
| 8. | ALA5225842 | A | Permeability across apical to basolateral side in human Caco-2 cells incubated for 120 mins by LC-MS analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA5225846 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 10. | ALA5225847 | A | Hepatic blood flow in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis relative to control | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 11. | ALA5225848 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 12. | ALA5225849 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 13. | ALA5225850 | A | Cmax in Sprague-Dawley rat at 3 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA5225851 | A | AUC in Sprague-Dawley rat at 3 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 15. | ALA5225852 | A | Oral bioavailability in Sprague-Dawley rat at 3 mg/kg measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5225853 | A | Half life in mouse at 30 mg/kg, po bid | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5225854 | A | Half life in mouse at 75 mg/kg, po bid | Mus musculus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!