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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5228999 B Displacement of BODIPY from APC-labelled human RORgammat LBD incubated for 15 mins by by LANCE detection analysis Homo sapiens 46 ALA5226347 single protein format Scientific Literature 2. ALA5229000 P Lipophilicity, log D of the compound at pH 7.4 46 ALA5226347 small-molecule physicochemical format Scientific Literature 3. ALA5229001 B Inhibition of RORgammat in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity incubated for 10 mins by luciferase reporter gene assay Homo sapiens 46 ALA5226347 cell-based format Scientific Literature 4. ALA5229002 B Inhibition of RORgammat in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity incubated for 10 mins by luciferase reporter gene assay relative to control Homo sapiens 42 ALA5226347 cell-based format Scientific Literature 5. ALA5229003 A Metabolic stability in human liver microsomes assessed as half life incubated for 5 to 30 mins by HPLC-MS/MS analysis Homo sapiens 6 ALA5226347 microsome format Scientific Literature 6. ALA5229004 A Metabolic stability in human liver assessed as intrinsic clearance incubated for 5 to 30 mins by HPLC-MS/MS analysis Homo sapiens 6 ALA5226347 tissue-based format Scientific Literature 7. ALA5229005 A Metabolic stability in human liver microsomes assessed as parent compound remaining measured at 60 mins by HPLC-MS/MS analysis Homo sapiens 6 ALA5226347 microsome format Scientific Literature 8. ALA5229006 P Solubility of compound in aqueous buffer at pH 7.4 2 ALA5226347 small-molecule physicochemical format Scientific Literature 9. ALA5229007 B Inhibition of human GAL4-fused RORgammat LBD transfected in HEK293T cell measured for 16 to 20 hrs by by dual-glo luciferase assay Homo sapiens 1 ALA5226347 cell-based format Scientific Literature 10. ALA5229008 B Inhibition of human GAL4-fused RORalpha LBD transfected in HEK293T cell measured for 16 to 20 hrs by by dual-glo luciferase assay Homo sapiens 1 ALA5226347 cell-based format Scientific Literature 11. ALA5229009 B Inhibition of human GAL4-fused RORbeta LBD transfected in HEK293T cell measured for 16 to 20 hrs by by dual-glo luciferase assay Homo sapiens 1 ALA5226347 cell-based format Scientific Literature 12. ALA5229010 A Half life in mouse at 0.3 mg/kg, iv measured at 2 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature 13. ALA5229011 A Half life in mouse at 1 mg/kg, po measured at 5 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature 14. ALA5229012 A Tmax in mouse at 0.3 mg/kg, iv measured at 2 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature 15. ALA5229013 A Tmax in mouse at 1 mg/kg, po measured at 5 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature 16. ALA5229014 A Cmax in mouse at 0.3 mg/kg, iv measured at 2 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature 17. ALA5229015 A Cmax in mouse at 1 mg/kg, po measured at 5 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature 18. ALA5229016 A Volume of distribution at steady state in mouse at 0.3 mg/kg, iv measured at 2 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature 19. ALA5229017 A Clearance in mouse at 0.3 mg/kg, iv measured at 2 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature 20. ALA5229018 A AUC (0 to t) in mouse at 0.3 mg/kg, iv measured at 2 to 1440 mins by LC-MS analysis Mus musculus 1 ALA5226347 organism-based format Scientific Literature