| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5240300 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 90 | cell-based format | Scientific Literature | ||
| 2. | ALA5240301 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate at 10 uM incubated for 90 mins by TopCount NXT counter based analysis relative to control | Homo sapiens | 90 | cell-based format | Scientific Literature | ||
| 3. | ALA5240302 | B | Agonist activity at N-terminal FLAG tagged human FFAR4 transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 90 | cell-based format | Scientific Literature | ||
| 4. | ALA5240303 | B | Agonist activity at N-terminal FLAG tagged human FFAR4 transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate at 10 uM incubated for 90 mins by TopCount NXT counter based analysis relative to control | Homo sapiens | 90 | cell-based format | Scientific Literature | ||
| 5. | ALA5240304 | P | Lipophilicity, logD of the compound | 10 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA5240305 | A | Metabolic stability in CD-1 mouse liver S9 fraction assessed as half-life at 2 uM measured upto 40 mins in the presence of NADPH by HPLC-MS analysis | Mus musculus | 10 | subcellular format | Scientific Literature | ||
| 7. | ALA5240306 | P | Solubility of the compound in PBS buffer at pH 7.4 | 12 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA5240308 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 Y12 mutant transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5240309 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 E65 mutant transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5240310 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 A66 mutant transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5240311 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 K259 mutant transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5240312 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 L262 mutant transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5240313 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 S8A mutant transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate by measuring fold decrease in potency incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5240314 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 S8A mutant transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate by measuring decrease in efficacy incubated for 90 mins by TopCount NXT counter based analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5240317 | B | Agonist activity at N-terminal FLAG tagged human FFAR1 A83F mutant transfected in African green monkey COS-7 cells assessed as accumulation of inositol phosphate by measuring fold change in potency incubated for 90 mins by TopCount NXT counter based analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
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