# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5257498 | Toxicity | Cytotoxicity against human MCF-10A cells assessed as cell viability incubated for 96 hrs by MTT assay | Homo sapiens | 69 | ALA5257024 | cell-based format | Scientific Literature | |
2. | ALA5257499 | Functional | Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay | Homo sapiens | 70 | ALA5257024 | cell-based format | Scientific Literature | |
3. | ALA5257500 | Functional | Antiproliferative activity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay | Homo sapiens | 70 | ALA5257024 | cell-based format | Scientific Literature | |
4. | ALA5257501 | Functional | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay | Homo sapiens | 70 | ALA5257024 | cell-based format | Scientific Literature | |
5. | ALA5257502 | Functional | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay | Homo sapiens | 70 | ALA5257024 | cell-based format | Scientific Literature | |
6. | ALA5257503 | Functional | Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay | Homo sapiens | 70 | ALA5257024 | cell-based format | Scientific Literature | |
7. | ALA5257504 | Functional | Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay | Homo sapiens | 70 | ALA5257024 | cell-based format | Scientific Literature | |
8. | ALA5257505 | Functional | Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by propidium iodide staining based fluorometer assay | Homo sapiens | 70 | ALA5257024 | cell-based format | Scientific Literature | |
9. | ALA5257506 | Binding | Inhibition of pig brain tubulin polymerization at 25 uM measured after 15 mins by fluorescence based turbidimetry | Sus scrofa | 10 | ALA5257024 | tissue-based format | Scientific Literature | |
10. | ALA5257508 | Binding | Induction of pig brain microtubule stabilization at 25 uM measured after 15 mins by fluorescence based turbidimetry | Sus scrofa | 11 | ALA5257024 | tissue-based format | Scientific Literature | |
11. | ALA5257509 | Binding | Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus infected Sf9 insect cells preincubated for 10 mins followed by ATP and MgCl2 addition measured after 60 mins by DELFIA/time-resolved fluorometric analysis | Homo sapiens | 11 | ALA5257024 | cell-based format | Scientific Literature | |
12. | ALA5257510 | Binding | Inhibition of full length mouse GST-tagged BRAF V600E mutant preincubated for 60 mins followed by addition of N-terminal His-tagged full length human MEK1 incubated for 25 mins in presence of ATP by ELISA assay | Mus musculus | 11 | ALA5257024 | assay format | Scientific Literature | |
13. | ALA5257511 | Functional | Reversal of multidrug resistance in mouse L5178Y cells transfected with human MDR1 assessed as reversal of rhodamine 123 accumulation at 50 ug/ml incubated for 30 mins by flow cytometry | Mus musculus | 10 | ALA5257024 | cell-based format | Scientific Literature | |
14. | ALA5257512 | Functional | Reversal of multidrug resistance in mouse L5178Y cells transfected with human MDR1 assessed as reversal of rhodamine 123 accumulation by measuring fluorescence activity ratio at 50 ug/ml incubated for 30 mins by flow cytometry | Mus musculus | 11 | ALA5257024 | cell-based format | Scientific Literature | |
15. | ALA5257513 | Functional | Reversal of multidrug resistance in mouse L5178Y cells transfected with human MDR1 assessed as reversal of rhodamine 123 accumulation at 5 ug/ml incubated for 30 mins by flow cytometry | Mus musculus | 10 | ALA5257024 | cell-based format | Scientific Literature | |
16. | ALA5257514 | Toxicity | Toxicity in mouse L5178Y cells transfected with human MDR1 at 50 ug/ml after short period of incubation by tryptan blue assay | Mus musculus | 10 | ALA5257024 | cell-based format | Scientific Literature |