# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5258677 | Binding | Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assay | Homo sapiens | 34 | ALA5257067 | cell-based format | Scientific Literature | |
2. | ALA5258684 | ADME | Unbound fraction in rat plasma | Rattus norvegicus | 2 | ALA5257067 | cell-free format | Scientific Literature | |
3. | ALA5258685 | ADME | Unbound fraction in human plasma | Homo sapiens | 2 | ALA5257067 | cell-free format | Scientific Literature | |
4. | ALA5258686 | ADME | Unbound fraction in rat brain | Rattus norvegicus | 2 | ALA5257067 | tissue-based format | Scientific Literature | |
5. | ALA5258687 | ADME | Permeability coefficient of compound in Sprague-Dawley rat at 0.25 mg/kg, iv administered as cassette dose | Rattus norvegicus | 1 | ALA5257067 | organism-based format | Scientific Literature | |
6. | ALA5258688 | ADME | Intrinsic clearance in human | Homo sapiens | 2 | ALA5257067 | assay format | Scientific Literature | |
7. | ALA5258689 | ADME | Intrinsic clearance in rat | Rattus norvegicus | 2 | ALA5257067 | assay format | Scientific Literature | |
8. | ALA5258691 | ADME | Plasma clearance in Sprague-Dawley rat at 0.25 mg/kg, iv administered as cassette dose | Rattus norvegicus | 1 | ALA5257067 | organism-based format | Scientific Literature | |
9. | ALA5258693 | ADME | Half life in Sprague-Dawley rat at 0.25 mg/kg, iv administered as cassette dose | Rattus norvegicus | 1 | ALA5257067 | organism-based format | Scientific Literature | |
10. | ALA5258695 | ADME | MRT in Sprague-Dawley rat at 0.25 mg/kg, iv administered as cassette dose | Rattus norvegicus | 1 | ALA5257067 | organism-based format | Scientific Literature | |
11. | ALA5258697 | ADME | Volume of distribution at steady state in Sprague-Dawley rat at 0.25 mg/kg, iv administered as cassette dose | Rattus norvegicus | 1 | ALA5257067 | organism-based format | Scientific Literature |