# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5256307 | Functional | Antiviral activity against SARS-CoV-2 BetaCoV/France/IDF0372/2020 infected human A549-ACE2 cells assessed as inhibition of viral replication by qRT-PCR analysis | Severe acute respiratory syndrome coronavirus 2 | 22 | ALA5252642 | organism-based format | Scientific Literature | |
2. | ALA5256308 | Toxicity | Cytotoxicity against human A549-ACE2 cells | Homo sapiens | 22 | ALA5252642 | cell-based format | Scientific Literature | |
3. | ALA5256309 | Functional | Antiviral activity against SARS-CoV-2 Omicron BA1 variant infected human A549-ACE2 cells assessed as inhibition of viral replication | Severe acute respiratory syndrome coronavirus 2 | 2 | ALA5252642 | organism-based format | Scientific Literature | |
4. | ALA5256310 | Toxicity | Selectivity index, ratio of CC50 for human A549-ACE2 cells to EC50 for antiviral activity against SARS-CoV-2 Omicron BA1 variant infected human A549-ACE2 cells | 15 | ALA5252642 | assay format | Scientific Literature | ||
5. | ALA5256311 | Binding | Inhibition of SARS-CoV-2 N-terminus His tagged nsp10/nsp16 complex expressed in Escherichia coli using [3H]SAM as substrate by scintillation proximity assay | Severe acute respiratory syndrome coronavirus 2 | 3 | ALA5252642 | assay format | Scientific Literature | |
6. | ALA5256312 | Binding | Inhibition of SARS-CoV-2 nsp14 guanine-N7-methyltransferase activity | Severe acute respiratory syndrome coronavirus 2 | 3 | ALA5252642 | single protein format | Scientific Literature | |
7. | ALA5256313 | Binding | Inhibition of wild type SARS-CoV2 main protease by measuring luciferase signal at 10 uM by reverse-nanoluciferase reporter assay | Severe acute respiratory syndrome coronavirus 2 | 2 | ALA5252642 | single protein format | Scientific Literature | |
8. | ALA5256314 | Binding | Inhibition of wild type SARS-CoV2 main protease by measuring luciferase signal at 0.02 to 125 uM by reverse-nanoluciferase reporter assay | Severe acute respiratory syndrome coronavirus 2 | 2 | ALA5252642 | single protein format | Scientific Literature | |
9. | ALA5256315 | Binding | Inhibition of SARS-CoV2 main protease C145A mutant by measuring luciferase signal at 0.02 to 125 uM by reverse-nanoluciferase reporter assay | Severe acute respiratory syndrome coronavirus 2 | 2 | ALA5252642 | assay format | Scientific Literature |